A
A.K. Khanna
Researcher at Central Drug Research Institute
Publications - 17
Citations - 404
A.K. Khanna is an academic researcher from Central Drug Research Institute. The author has contributed to research in topics: Vibration & Deflection (engineering). The author has an hindex of 12, co-authored 16 publications receiving 380 citations.
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Indole-based fibrates as potential hypolipidemic and antiobesity agents.
TL;DR: Effects such as an increase in lecithin cholesterol acyl-transferase (LCAT) enzyme level and increased receptor mediated catabolism of I(131)-low density lipoproteins (LDL) confirm and reinforce the efficacy of both of these compounds as a new class of dual-acting hypolipidemic and antiobesity agents.
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Synthesis and anti-inflammatory activity of novel biscoumarin-chalcone hybrids.
Koneni V. Sashidhara,Manoj Kumar,Ram K. Modukuri,Ravi Sonkar,Gitika Bhatia,A.K. Khanna,Shivika Rai,Rakesh Shukla +7 more
TL;DR: A series of synthesized novel biscoumarin-chalcone hybrids were evaluated for their anti-inflammatory and antioxidant activity and constitute an interesting template for the design of new therapeutic tools against inflammation.
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Syntheses and evaluation of glucosyl aryl thiosemicarbazide and glucosyl thiosemicarbazone derivatives as antioxidant and anti-dyslipidemic agents.
Samir Ghosh,Samir Ghosh,Anup Kumar Misra,Anup Kumar Misra,Gitika Bhatia,Mahaboob Khan,A.K. Khanna +6 more
TL;DR: A series of N-per-O-acetyl-glucosyl arylthiosemicarbazide and thioseMICarbazone derivatives have been synthesized and evaluated for their in vivo anti-dyslipidemic and in vitro antioxidant activities.
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Novel Coumarin derivatives as potential antidyslipidemic agents
TL;DR: A series of novel benzocoumarin derivatives were synthesized and evaluated for their in vivo antidyslipidemic and in vitro antioxidant activities.
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Antidyslipidemic and antioxidant activity of the constituents isolated from the leaves of Calophyllum inophyllum.
Janki Prasad,Atul Shrivastava,A.K. Khanna,Gitika Bhatia,Shailendra K. Awasthi,Tadigoppula Narender +5 more
TL;DR: In continuation of the drug discovery program on Indian medicinal plants, bioactive compounds isolated from the leaves of Calophyllum inophyllums showed dose dependent lipid lowering activity in in vivo experiments and also showed good in vitro antioxidant activity.