A
A Labigne
Researcher at French Institute of Health and Medical Research
Publications - 13
Citations - 2788
A Labigne is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Escherichia coli & Helicobacter pylori. The author has an hindex of 9, co-authored 13 publications receiving 2695 citations.
Papers
More filters
Journal ArticleDOI
Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island
Jérôme Viala,Catherine Chaput,Ivo G Boneca,Ana Cardona,Stephen E. Girardin,Anthony P. Moran,Rafika Athman,Sylvie Mémet,Michael R Huerre,Anthony J. Coyle,Peter S. DiStefano,Philippe J. Sansonetti,A Labigne,John Bertin,Dana J. Philpott,Dana J. Philpott,Richard L. Ferrero,Richard L. Ferrero +17 more
TL;DR: It is proposed that sensing of H. pylori by Nod1 represents a model for host recognition of noninvasive pathogens as well as an intracellular pathogen-recognition molecule with specificity for Gram-negative peptidoglycan.
Journal ArticleDOI
Rapid and specific detection of the pap, afa, and sfa adhesin-encoding operons in uropathogenic Escherichia coli strains by polymerase chain reaction.
TL;DR: The PCR method, which is highly specific and easier to perform than the hybridization method, is a powerful genotypic assay for detection of adhesin-encoding operons and can be recommended for clinical use to detect virulent urinary E. coli strains, as well as for epidemiological studies.
Journal ArticleDOI
The GroES homolog of Helicobacter pylori confers protective immunity against mucosal infection in mice
TL;DR: A protein belonging to the GroES class of heat shock proteins that was shown to induce protective immunity was reported, identified as potential components of a future H. pylori subunit vaccine.
Journal ArticleDOI
Expression of Helicobacter pylori urease genes in Escherichia coli grown under nitrogen-limiting conditions.
TL;DR: Nine H. pylori urease genes were identified and ureA, ureB,UreC, UreF, uREG, and UreH were shown to be required for ure enzyme expression in E. coli, as mutations in each of these genes led to negative phenotypes.
Journal ArticleDOI
Construction of isogenic urease-negative mutants of Helicobacter pylori by allelic exchange.
TL;DR: Generation of stable, genetically engineered urease mutants of H. pylori will be useful for addressing the role of ure enzyme in the pathogenesis ofH.