A Ly

TL;DR: It is concluded that there is no convincing evidence for praziquantel‐resistant S. mansoni in Senegal, and that the low cure rates can be attributed to high initial worm loads and intense transmission in this area.

TL;DR: In conclusion, infection by S. mansoni affects susceptibility to malaria, but this can vary according to the intensity of parasite load, and the immunological mechanisms underlying this dual effect need to be further explored.

TL;DR: Two treatments with praziquantel (PZQ) 40 mg/kg, 40 d apart, were sufficient to give an adequate cure rate and high reductions in the intensity of infection in a recently established Schistosoma mansoni focus in the Senegal River Basin.

TL;DR: There is evidence that age, sex and place of residence determine exposure but none to suggest that exposure had an influence on the relationship between these factors and intensity of infection.

TL;DR: It is indicated that malaria co-infection can both influence the acquired specific immune response to schistosome antigens and unbalance the regulation of inflammatory factors closely involved inschistosomiasis pathology.