Aamir Ahmad

TL;DR: It is demonstrated that NHERF-1 is necessary for PTH-mediated inhibition of Na+,K+-ATPase activity and that the inhibition is mediated through the PDZ1, not PDZ2, domain.

TL;DR: A novel role of genistein and other isoflavones in the potentiation of radiation therapy, epigenetic regulation of key tumor suppressors and oncogenes, and the modulation of miRNAs, epithelial-to-mesenchymal transition, and cancer stem cells is indicated, which has renewed the interest of cancer researchers in this class of anticancer compounds.

TL;DR: Mechanistic studies revealed that ETV4 directly regulates the expression of Cyclin D1 CCND1, a protein crucial for cell-cycle progression from G1- to S-phase, which provides the first experimental evidence for a functional role of ETV 4 in pancreatic cancer growth and cell- cycle progression.

TL;DR: Latest updates on the evidences that further highlight an association between various signaling pathways and EMT are provided, with a focus on therapeutic targets that may have the potential to reverse EMT.

TL;DR: The results clearly suggest the importance of miRNAs in the regulation of CSLC characteristics, and may serve as novel targets for therapy.