A
Aamir Ahmad
Researcher at University of Alabama at Birmingham
Publications - 257
Citations - 15418
Aamir Ahmad is an academic researcher from University of Alabama at Birmingham. The author has contributed to research in topics: Cancer & Cancer stem cell. The author has an hindex of 63, co-authored 251 publications receiving 13404 citations. Previous affiliations of Aamir Ahmad include Aligarh Muslim University & Hamad Medical Corporation.
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Book ChapterDOI
MicroRNA Targeted Therapy for Overcoming Drug Resistance, Reversal of EMT and Elimination of Cancer Stem Cells in Prostate and Pancreatic Cancer
TL;DR: Targeting miRNAs by synthetic agents, nutraceuticals, or synthetic oligonucleotide delivery could become a promising approach for overcoming drug resistance, reversal of EMT, and elimination of CSCs, which would likely lead successful treatment of outcome in patients diagnosed with pancreatic and prostate cancers.
Proceedings ArticleDOI
Abstract 2698: Improved therapeutic activity of Isoflavone-G2535 and Docetaxel combination in hormone refractory prostate cancer
TL;DR: In vitro and in vivo preclinical evidence of chemo-sensitization of CRPC cells to the most clinically useful therapeutic agent, Docetaxel (Taxotere) by G2535, an isoflavone that attenuates AR signaling is presented.
Journal ArticleDOI
Role of JNK and NF-κB in mediating the effect of combretastatin A-4 and brimamin on endothelial and carcinoma cells
Katharina Mahal,Aamir Ahmad,Seema Sethi,Marcus Resch,Ralf Ficner,Fazlul H. Sarkar,Rainer Schobert,Bernhard Biersack +7 more
TL;DR: The data indicate that cellular JNK and Rho kinase activities are crucial for the cytotoxic and cytoskeleton reorganizing effects of brimamin on endothelial cells, making brimamin a promising candidate vascular-disrupting agent.
Journal ArticleDOI
Metal-based anticancer agents: targeting androgen-dependent and androgen-independent prostate and COX-positive pancreatic cancer cells by phenanthrenequinone semicarbazone and its metal complexes
Zahra Afrasiabi,Rosana Almudhafar,Di Xiao,Ekkehard Sinn,Amitava Choudhury,Aamir Ahmad,Alok Vyas,Fazlul H. Sarkar,Subhash Padhye,Subhash Padhye +9 more
TL;DR: In vitro antiproliferative activity of 9,10-phenanthrenequinone semicarbazone and its transition metal complexes revealed that they were effective against androgen receptor-positive/negative prostate cancer cells as well as COX-positive pancreatic BxPC-3 cancer cell line.
Journal ArticleDOI
Sex differences in cardiopulmonary effects of acute bromine exposure.
Juan Xavier Masjoan Juncos,Shazia Shakil,Aamir Ahmad,Nithya Mariappan,Iram Zafar,Wayne E. Bradley,Louis J. Dell'Italia,Aftab Ahmad,Shama Ahmad +8 more
TL;DR: It is demonstrated that acute high-concentration bromine inhalation is fatal, and cardiac injury and dysfunction play an important role in Br>2> toxicity in males, and the mean arterial pressure was not significantly elevated in females.