A
Aamir Ahmad
Researcher at University of Alabama at Birmingham
Publications - 257
Citations - 15418
Aamir Ahmad is an academic researcher from University of Alabama at Birmingham. The author has contributed to research in topics: Cancer & Cancer stem cell. The author has an hindex of 63, co-authored 251 publications receiving 13404 citations. Previous affiliations of Aamir Ahmad include Aligarh Muslim University & Hamad Medical Corporation.
Papers
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Journal ArticleDOI
Rosin Surfactant QRMAE Can Be Utilized as an Amorphous Aggregate Inducer: A Case Study of Mammalian Serum Albumin.
Mohd Ishtikhar,Tajjali Ilm Chandel,Aamir Ahmad,Mohd. Sajid Ali,Hamad A. Al-lohadan,Ayman M. Atta,Rizwan Hasan Khan +6 more
TL;DR: It was observed that a suitable molar ratio of protein to QRMAE surfactant enthusiastically induces amorphous aggregate formation at a pH above two units of pI, which can be used for the design of novel biomolecules or drugs with the ability to neutralize factor responsible for the aggregate formation in addition to various other industrial applications.
Journal ArticleDOI
Apogossypolone, derivative of gossypol, mobilizes endogenous copper in human peripheral lymphocytes leading to oxidative DNA breakage
Haseeb Zubair,Husain Yar Khan,M.F. Ullah,M.F. Ullah,Aamir Ahmad,Aamir Ahmad,Daocheng Wu,S.M. Hadi +7 more
TL;DR: It is well established that tissue, cellular and serum copper levels are considerably elevated in various malignancies, therefore, cancer cells may be subject to greater electron transfer between copper ions and gossypol/apogOSSypolone to generate reactive oxygen species responsible for DNA cleavage.
Journal ArticleDOI
Mobilization of Nuclear Copper by Green Tea Polyphenol Epicatechin-3-Gallate and Subsequent Prooxidant Breakage of Cellular DNA: Implications for Cancer Chemotherapy
TL;DR: It is shown that epicatechin-3-gallate degrades DNA in cell nuclei, which can be inhibited by neocuproine, suggesting mobilization of nuclear copper in this reaction as well, and indicative of ROS generation, possibly through mobilization of endogenous copper ions.
Book ChapterDOI
Epigenetics in Personalized Management of Lung Cancer.
TL;DR: In this chapter, a succinct review of methylation and acetylation events that have profound effect on the eventual expression of oncogenes and the suppression of tumor suppressors are provided.
Journal ArticleDOI
A novel Ru(II) complex derived from hydroxydiamine as a potential antitumor agent: Synthesis and Structural Characterization
Mohammad Azam,Ismail Warad,Saud I. Al-Resayes,Mohammad Shakir,M.F. Ullah,Aamir Ahmad,Fazlul H. Sarkar +6 more
TL;DR: In this paper, a novel Ru(II)-Schiff base complex has been synthesized by the interaction of ligand, 1,3-bis{[(E)-(2-chlorophenyl)methylidene]amino}-2-propanol, L with [RuCl2(PPh3)3].