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Abhishek Yadav
Researcher at Defence Research and Development Establishment
Publications - 22
Citations - 829
Abhishek Yadav is an academic researcher from Defence Research and Development Establishment. The author has contributed to research in topics: Arsenic toxicity & Oxidative stress. The author has an hindex of 13, co-authored 18 publications receiving 702 citations. Previous affiliations of Abhishek Yadav include Defence Research and Development Organisation & University of Texas at Arlington.
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Effects of sub-acute exposure to TiO2, ZnO and Al2O3 nanoparticles on oxidative stress and histological changes in mouse liver and brain.
TL;DR: A significant increase in dopamine and norepinephrine levels in brain cerebral cortex and increased brain oxidative stress suggest neurotoxic potential of these nanoparticles.
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Curcumin encapsulated in chitosan nanoparticles: a novel strategy for the treatment of arsenic toxicity.
TL;DR: The results indicate that ECNPs have better antioxidant and chelating potential (even at the lower dose of 1.5 mg/kg) compared to free curcumin at 15mg/kg, and indicates their neuroprotective efficacy.
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Therapeutic efficacy of silymarin and naringenin in reducing arsenic-induced hepatic damage in young rats.
TL;DR: Silymarin or naringenin administration increased GSH levels and was beneficial in the recovery of altered SOD and catalase activity besides significantly reducing blood and tissue arsenic concentration, pointing to the antioxidant potential of these flavonoids.
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MiADMSA reverses impaired mitochondrial energy metabolism and neuronal apoptotic cell death after arsenic exposure in rats
TL;DR: The results indicate that arsenic exposure induced free radical generation in rat neuronal cells, which diminished mitochondrial potential and enzyme activities of all the complexes of the electron transport chain, and differential responses towards arsenic.
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Preferential DNA cleavage under anaerobic conditions by a DNA-binding ruthenium dimer
TL;DR: The dioxygen concentration regulates the degree to which the carbon radical forms and thus regulates the DNA cleavage activity, and a carbon-based radical species is implicated in the cleavage action.