scispace - formally typeset
A

Abrahan Hernández-Hernández

Researcher at Karolinska Institutet

Publications -  28
Citations -  924

Abrahan Hernández-Hernández is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Synaptonemal complex & Meiosis. The author has an hindex of 13, co-authored 26 publications receiving 723 citations. Previous affiliations of Abrahan Hernández-Hernández include National Autonomous University of Mexico.

Papers
More filters
Journal ArticleDOI

Meiosis-specific cohesin mediates homolog recognition in mouse spermatocytes

TL;DR: It is shown that homolog recognition or association initiates upon entry into meiotic prophase before axis assembly and double-strand break (DSB) formation, suggesting the intriguing possibility that homology recognition is achieved primarily by searching for homology in the chromosome architecture as defined by meiosis-specific cohesin rather than in the DNA sequence itself.
Journal ArticleDOI

MAJIN Links Telomeric DNA to the Nuclear Membrane by Exchanging Telomere Cap.

TL;DR: A positive feedback between telomere attachment and chromosome movement is uncovered, revealing a comprehensive regulatory network underlying meiosis-specific telomeres function in mammals.
Journal ArticleDOI

STAG3‐mediated stabilization of REC8 cohesin complexes promotes chromosome synapsis during meiosis

TL;DR: It is found that the three different α‐kleisins present in meiotic cells show different dosage‐dependent requirements for STAG3 and thatSTAG3‐REC8 cohesin complexes have a critical role in supporting meiotic chromosome structure and functions.
Journal ArticleDOI

Human disease locus discovery and mapping to molecular pathways through phylogenetic profiling.

TL;DR: Focusing on proteins coevolved with the microphthalmia‐associated transcription factor (MITF), the Notch pathway suppressor of hairless (RBP‐Jk/SuH) transcription factor is identified, and it is shown that RBP‐JK functions as an MITF cofactor.