Abukar Ali

TL;DR: The augmented infection model more closely resembles the natural situation and establishes the role of resident environmental microflora in the initiation of disease by an invading pathogen.

TL;DR: IL-1Ra treatment significantly aggravated S. aureus induced septic arthritis and increased the mortality in these mice, and in line with the data from clinical arthritis, both histological and radiological signs of sepsis were more pronounced in IL-1 Ra treated group compared to controls.

TL;DR: Permanent reduction in joint function is a severe postinfectious complication in patients with Staphylococcus aureus septic arthritis and this study undertook this study to determine whether it might be caused by persistent joint inflammation after the adequate eradication of bacteria by antibiotics.

TL;DR: In this article, the interplay between bacterial virulence factors and host immune response, which decides the disease outcome, was studied in Staphylococcus aureus septic arthritis.

TL;DR: CTLA4-Ig therapy significantly increased the susceptibility to S. aureus septic arthritis in mice, whereas anti-TNF therapy deteriorated host bacterial clearance, resulting in more-severe weight loss and kidney abscesses.