A
Abul Arif
Researcher at Cleveland Clinic Lerner Research Institute
Publications - 25
Citations - 1633
Abul Arif is an academic researcher from Cleveland Clinic Lerner Research Institute. The author has contributed to research in topics: EPRS & Phosphorylation. The author has an hindex of 17, co-authored 25 publications receiving 1417 citations. Previous affiliations of Abul Arif include Emory University.
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The GAIT system: a gatekeeper of inflammatory gene expression
TL;DR: Repression of a post-transcriptional regulon by the GAIT system might contribute to the resolution of chronic inflammation.
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Target-selective protein S-nitrosylation by sequence motif recognition
TL;DR: Results reveal an elusive parallel between protein S-nitrosylation and phosphorylation, namely, stimulus-dependent posttranslational modification of selected targets by primary sequence motif recognition.
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Macromolecular complexes as depots for releasable regulatory proteins
TL;DR: A novel function of multi-component complexes as depots for regulatory proteins that, upon release, acquire new auxiliary functions is proposed and it is proposed that component release is inducible and context-dependent.
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DAPK-ZIPK-L13a Axis Constitutes a Negative-Feedback Module Regulating Inflammatory Gene Expression
TL;DR: It is proposed that the DAPK-ZIPK-L13a axis forms a unique regulatory module that first represses, then repermits inflammatory gene expression, and that pathway defects may contribute to chronic inflammatory disorders.
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WHEP domains direct noncanonical function of glutamyl-Prolyl tRNA synthetase in translational control of gene expression
TL;DR: Total reconstitution from purified components indicates that the four GAIT proteins are necessary and sufficient for self-assembly of a functional complex and establishes the essentiality of WHEP domains in the noncanonical function of EPRS in regulating inflammatory gene expression.