A
Abul K. Abbas
Researcher at University of California, San Francisco
Publications - 252
Citations - 36528
Abul K. Abbas is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: T cell & Antigen. The author has an hindex of 88, co-authored 251 publications receiving 34965 citations. Previous affiliations of Abul K. Abbas include American Association for the Advancement of Science & Brigham and Women's Hospital.
Papers
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Journal ArticleDOI
Functional diversity of helper T lymphocytes.
TL;DR: The existence of subsets of CD4+ helper T lymphocytes that differ in their cytokine secretion patterns and effector functions provides a framework for understanding the heterogeneity of normal and pathological immune responses.
Book
Cellular and Molecular Immunology
TL;DR: Cellular and molecular immunology , Cellular and molecular Immunology , کتابخانه الکرونیک و دیجیتال - آذرسا
Journal ArticleDOI
Natural versus adaptive regulatory T cells.
TL;DR: In this article, the existence of two subsets of CD4+ T(Reg) cells, natural and adaptive, was shown to differ in terms of their development, specificity, mechanism of action and dependence on T-cell receptor and co-stimulatory signalling.
Journal ArticleDOI
Homeostasis and Self-Tolerance in the Immune System: Turning Lymphocytes off
Luk Van Parijs,Abul K. Abbas +1 more
TL;DR: Here, recent advances in understanding of the molecular bases and physiologic roles of the mechanisms of immune homeostasis are examined and several regulatory mechanisms function to terminate responses to foreign antigens.
Journal ArticleDOI
Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagement.
TL;DR: It is shown that the induction of T cell anergy in vivo is due to an abortive T cell response that requires recognition of B7 molecules, since blocking B7 maintains T cells in an unactivated but functionally competent state.