A
Adam Armada‐Moreira
Researcher at Instituto de Medicina Molecular
Publications - 8
Citations - 204
Adam Armada‐Moreira is an academic researcher from Instituto de Medicina Molecular. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 2, co-authored 4 publications receiving 49 citations. Previous affiliations of Adam Armada‐Moreira include University of Lisbon & Aarhus University.
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Journal ArticleDOI
Going the Extra (Synaptic) Mile: Excitotoxicity as the Road Toward Neurodegenerative Diseases.
Adam Armada‐Moreira,Adam Armada‐Moreira,Adam Armada‐Moreira,Joana Gomes,Joana Gomes,Carolina Campos Pina,Carolina Campos Pina,Oksana K Savchak,Oksana K Savchak,Joana Gonçalves-Ribeiro,Joana Gonçalves-Ribeiro,Nádia Rei,Nádia Rei,Sara Pinto,Sara Pinto,Tatiana P. Morais,Robertta Silva Martins,Filipa F Ribeiro,Filipa F Ribeiro,Ana M. Sebastião,Ana M. Sebastião,Vincenzo Crunelli,Vincenzo Crunelli,Sandra H. Vaz,Sandra H. Vaz +24 more
TL;DR: With the understanding that excitotoxicity is a common denominator in neurodegenerative diseases and other disorders, a new perspective on therapy can be considered, where the targets are not specific symptoms, but the underlying cellular phenomena of the disease.
Journal ArticleDOI
Organic electrochemical neurons and synapses with ion mediated spiking
Padinhare Cholakkal Harikesh,Chi-Yuan Yang,Deyu Tu,Jennifer Y. Gerasimov,Abdul Manan Dar,Adam Armada‐Moreira,Matteo Massetti,Renee Kroon,David Bliman,Roger Olsson,Eleni Stavrinidou,Magnus Berggren,Simone Fabiano +12 more
TL;DR: The first organic electrochemical neurons (OECNs) with ion-modulated spiking, based on all-printed complementary OEC transistors, were reported in this article .
Journal ArticleDOI
On the Assembly of Microreactors with Parallel Enzymatic Pathways.
Adam Armada‐Moreira,Adam Armada‐Moreira,Adam Armada‐Moreira,Bo Thingholm,Kristine Andreassen,Ana M. Sebastião,Ana M. Sebastião,Sandra H. Vaz,Sandra H. Vaz,Brigitte Städler +9 more
TL;DR: The successful co‐encapsulation of two enzymatic pathways with up to five enzymes into compartmentalized microreactors is reported, representing a relevant advancement in encapsulated catalysis toward the assembly of therapeutic cell mimics.
Journal ArticleDOI
Multicompartment Microreactors Prevent Excitotoxic Dysfunctions In Rat Primary Cortical Neurons.
Adam Armada‐Moreira,Adam Armada‐Moreira,Adam Armada‐Moreira,Joana E. Coelho,Luísa V. Lopes,Ana M. Sebastião,Ana M. Sebastião,Brigitte Städler,Sandra H. Vaz,Sandra H. Vaz +9 more
TL;DR: It is demonstrated that platinum nanoparticle‐based microreactors are compatible with rat primary cortical neurons, show high levels of neuronal membrane interaction, and are able to improve cell survival and neuronal activity when neurons are exposed to H2O2 or NH4+.
Journal ArticleDOI
Manganese dioxide nanosheet-containing reactors as antioxidant support for neuroblastoma cells.
Oksana K Savchak,Nanyi Wang,Miguel A. Ramos-Docampo,Paula de Dios Andres,Ana M. Sebastião,Filipa F Ribeiro,Adam Armada‐Moreira,Brigitte Städler,Sandra H. Vaz +8 more
TL;DR: Manganese dioxide nanosheets (MnO2-NSs) are used as catalytically active entities that have superoxide dismutase- like and catalase-like activities that were able to assist SH-SY5Y neuroblastoma cells when stressed with H2O2 and advanced the use of bottom-up synthetic biology concepts in neuroscience.