A
Adrian Park
Researcher at Imperial College London
Publications - 15
Citations - 3144
Adrian Park is an academic researcher from Imperial College London. The author has contributed to research in topics: Appetite & Oxyntomodulin. The author has an hindex of 11, co-authored 12 publications receiving 2984 citations. Previous affiliations of Adrian Park include Hammersmith Hospital.
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Journal ArticleDOI
Oxyntomodulin Suppresses Appetite and Reduces Food Intake in Humans
Mark Cohen,Sandra M. Ellis,Carel W. le Roux,Rachel L. Batterham,Adrian Park,Michael Patterson,Gary Frost,Mohammad A. Ghatei,Stephen R. Bloom +8 more
TL;DR: Elevated levels of endogenous OXM associated with disorders of the gastrointestinal tract may contribute to anorexia, and central injection of OXM reduces food intake and weight gain in rodents.
Journal ArticleDOI
Pancreatic polypeptide reduces appetite and food intake in humans.
Rachel L. Batterham,C. W. le Roux,Mark Cohen,Adrian Park,Sandra M. Ellis,Michael Patterson,Gary Frost,M. A. Ghatei,Stephen R. Bloom +8 more
TL;DR: The data demonstrates that PP causes a sustained decrease in both appetite and food intake, which suggests that PP may act as a circulating factor that regulates food intake.
Journal ArticleDOI
Subcutaneous Oxyntomodulin Reduces Body Weight in Overweight and Obese Subjects: A Double-Blind, Randomized, Controlled Trial
Katie Wynne,Adrian Park,Caroline J. Small,Michael Patterson,Sandra M. Ellis,Kevin G. Murphy,Alison M. Wren,Gary Frost,Karim Meeran,Mohammad A. Ghatei,Stephen R. Bloom +10 more
TL;DR: Oxyntomodulin treatment resulted in weight loss and a change in the levels of adipose hormones consistent with a loss of adipOSE tissue, and represents a potential therapy for obesity.
Ghrelin increases food intake in obese as well as lean subjects
Druce,Alison M. Wren,Adrian Park,J E Milton,Michael Patterson,Gary Frost,M. A. Ghatei,Caroline J. Small,S.R. Bloom +8 more
TL;DR: Ghrelin infusion increased food intake in obese as well as lean subjects as discussed by the authors, and increased palatability of food in the obese group only (mean increase 36.6±9.4%, P<0.01 in both cases.)
Journal ArticleDOI
Peptide YY3-36 and glucagon-like peptide-17-36 inhibit food intake additively.
Nicola M. Neary,Caroline J. Small,Maralyn Druce,Adrian Park,Sandra M. Ellis,Nina M. Semjonous,C. L. Dakin,Karin Filipsson,Fang Wang,Aysha Kent,Gary Frost,Mohammad A. Ghatei,Stephen R. Bloom +12 more
TL;DR: PYY(3-36) and GLP-1(7-36), cosecreted after a meal, may inhibit food intake additively and is studied in rodents and man.