K
Katie Wynne
Researcher at University of Newcastle
Publications - 67
Citations - 4266
Katie Wynne is an academic researcher from University of Newcastle. The author has contributed to research in topics: Medicine & Pregnancy. The author has an hindex of 17, co-authored 50 publications receiving 3854 citations. Previous affiliations of Katie Wynne include John Hunter Hospital & Charing Cross Hospital.
Papers
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Journal ArticleDOI
Dissociable Deficits in the Decision-Making Cognition of Chronic Amphetamine Abusers, Opiate Abusers, Patients with Focal Damage to Prefrontal Cortex, and Tryptophan-Depleted Normal Volunteers: Evidence for Monoaminergic Mechanisms
Robert D. Rogers,Barry J. Everitt,Alex Baldacchino,Alison J. Blackshaw,Rachel Swainson,Katie Wynne,N B Baker,J.E. Hunter,T. Carthy,E Booker,M. London,John Francis William Deakin,Barbara J. Sahakian,Trevor W. Robbins +13 more
TL;DR: It is suggested that chronic amphetamine abusers show similar decision-making deficits to those seen after focal damage to orbitofrontal PFC, which may reflect altered neuromodulation of the orbitof prefrontal PFC and interconnected limbic-striatal systems by both the ascending 5-HT and mesocortical dopamine projections.
Journal ArticleDOI
Attenuated peptide YY release in obese subjects is associated with reduced satiety.
C. W. le Roux,Rachel L. Batterham,Simon Aylwin,Michael Patterson,Cynthia-Michelle Borg,Katie Wynne,Aysha Kent,Royce P Vincent,James Gardiner,M. A. Ghatei,Stephen R. Bloom +10 more
TL;DR: Obese subjects have a PYY deficiency that would reduce satiety and could thus reinforce their obesity, and fasting and postprandial endogenous plasma PYY levels were attenuated in obese humans and rodents.
Journal ArticleDOI
Subcutaneous Oxyntomodulin Reduces Body Weight in Overweight and Obese Subjects: A Double-Blind, Randomized, Controlled Trial
Katie Wynne,Adrian Park,Caroline J. Small,Michael Patterson,Sandra M. Ellis,Kevin G. Murphy,Alison M. Wren,Gary Frost,Karim Meeran,Mohammad A. Ghatei,Stephen R. Bloom +10 more
TL;DR: Oxyntomodulin treatment resulted in weight loss and a change in the levels of adipose hormones consistent with a loss of adipOSE tissue, and represents a potential therapy for obesity.
Journal ArticleDOI
Hormonal Regulation of Food Intake
TL;DR: The peripheral hormones and central neuronal pathways that contribute to control of appetite and food intake and energy expenditure are discussed.
Journal ArticleDOI
Oxyntomodulin increases energy expenditure in addition to decreasing energy intake in overweight and obese humans: a randomised controlled trial
TL;DR: Data supports the role of oxyntomodulin as a potential anti-obesity therapy and increases energy expenditure while reducing energy intake resulting in negative energy balance.