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Adriele Prina-Mello
Researcher at Trinity College, Dublin
Publications - 146
Citations - 5781
Adriele Prina-Mello is an academic researcher from Trinity College, Dublin. The author has contributed to research in topics: Medicine & Computer science. The author has an hindex of 36, co-authored 125 publications receiving 4405 citations. Previous affiliations of Adriele Prina-Mello include IMDEA & University College Dublin.
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Journal ArticleDOI
Magnetic Nanoparticles in Cancer Theranostics.
TL;DR: This review provides state of the art of the nanotechnological applications for cancer therapy and advances a novel concept of personalized nanomedical theranostic therapy using iron oxide magnetic nanoparticles in conjunction with MRI imaging.
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Length-Dependent Retention of Carbon Nanotubes in the Pleural Space of Mice Initiates Sustained Inflammation and Progressive Fibrosis on the Parietal Pleura
Fiona Murphy,Craig A Poland,Rodger Duffin,Khuloud T. Al-Jamal,Khuloud T. Al-Jamal,Hanene Ali-Boucetta,Antonio Nunes,Fiona Byrne,Adriele Prina-Mello,Yuri Volkov,Shouping Li,Stephen J. Mather,Alberto Bianco,Maurizio Prato,William MacNee,William A Wallace,Kostas Kostarelos,Ken Donaldson +17 more
TL;DR: The data confirm the hypothesis that, although a proportion of all deposited particles passes through the pleura, the pathogenicity of long CNTs and other fibers arises as a result of length-dependent retention at the stomata on the parietal pleura.
Journal ArticleDOI
Nanomedicine applied to translational oncology: A future perspective on cancer treatment
Lisa Bregoli,Dania Movia,James D. Gavigan-Imedio,Joanne Lysaght,John V. Reynolds,Adriele Prina-Mello +5 more
TL;DR: Both clinically available anti-cancer nanomedicines and those en route to future clinical application are discussed, with a focus on their increased performance versus conventional molecular anticancer therapies.
Journal ArticleDOI
Efficient treatment of breast cancer xenografts with multifunctionalized iron oxide nanoparticles combining magnetic hyperthermia and anti-cancer drug delivery
Susanne Kossatz,Julia Grandke,Pierre Couleaud,Pierre Couleaud,Alfonso Latorre,Alfonso Latorre,Antonio Aires,Antonio Aires,Kieran Crosbie-Staunton,Robert Ludwig,Heidi Dähring,Volker Ettelt,Ana Lazaro-Carrillo,Macarena Calero,Macarena Calero,Maha Sader,José Courty,Yuri Volkov,Yuri Volkov,Adriele Prina-Mello,Adriele Prina-Mello,Angeles Villanueva,Angeles Villanueva,Álvaro Somoza,Álvaro Somoza,Aitziber L. Cortajarena,Aitziber L. Cortajarena,Rodolfo Miranda,Rodolfo Miranda,Ingrid Hilger +29 more
TL;DR: The therapeutic effects of breast cancer magneticHyperthermia could be strongly enhanced by the combination of MF66 functionalized with N6L and DOX and magnetic hyperthermia and represents a straightforward strategy for translation into the clinical practice when injecting nanoparticles intratumorally.
Journal ArticleDOI
Measuring particle size distribution of nanoparticle enabled medicinal products, the joint view of EUNCL and NCI-NCL. A step by step approach combining orthogonal measurements with increasing complexity
TL;DR: A multi‐step approach of incremental complexity to measure particle size distribution and size stability of NEPs, consisting of a quick preliminary step to assess sample integrity and stability by low resolution techniques (pre‐screening), followed by the combination of complementary high resolution sizing measurements performed both in simple buffers and in complex biological media.