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Afrânio Lineu Kritski
Researcher at Federal University of Rio de Janeiro
Publications - 216
Citations - 3852
Afrânio Lineu Kritski is an academic researcher from Federal University of Rio de Janeiro. The author has contributed to research in topics: Tuberculosis & Mycobacterium tuberculosis. The author has an hindex of 30, co-authored 198 publications receiving 3376 citations. Previous affiliations of Afrânio Lineu Kritski include Universidade Federal de Minas Gerais.
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Journal ArticleDOI
Phenotypes of lung mononuclear phagocytes in HIV seronegative tuberculosis patients: evidence for new recruitment and cell activation
José Roberto Lapa e Silva,Cristiane Linhares,Neio Boechat,Lorena Rego,Maria da Gloria Bonecini Almeida,Afrânio Lineu Kritski,John L. Ho +6 more
TL;DR: Immunostaining the phenotype of mononuclear phagocytes obtained from lungs of patients with active tuberculosis suggests that despite recruitment of monocytes probably from the peripheral blood and local cell activation, host defense of the resident lung cells is insufficient to control M. tuberculosis.
Journal ArticleDOI
Clinical impact and cost analysis of the use of either the Xpert MTB Rif test or sputum smear microscopy in the diagnosis of pulmonary tuberculosis in Rio de Janeiro, Brazil.
Anália Zuleika de Castro,Adriana S. R. Moreira,Jaqueline da Silva Oliveira,Paulo Albuquerque da Costa,Carolyne Lalucha Alves Lima Da Graça,Maurício de Andrade Pérez,Afrânio Lineu Kritski,Maria Claudia Vater +7 more
TL;DR: Compared with SSM, Xpert test showed a greater sensitivity, but it also had a time delay with respect to treatment initiation and a higher mean cost per examination.
Journal ArticleDOI
Modelling the impact of chest X-ray and alternative triage approaches prior to seeking a tuberculosis diagnosis.
Abu A. M. Shazzadur Rahman,Ivor Langley,Rafael Mello Galliez,Afrânio Lineu Kritski,Ewan Tomeny,S. Bertel Squire +5 more
TL;DR: A model for the impact assessment of alternative triage approaches for tuberculosis, with or without X-ray, based on data from Porto Alegre City, Brazil demonstrates its usefulness in informing policy in a typical high burden setting for tuberculosis.
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An ensemble approach for supporting the respiratory isolation of presumed tuberculosis inpatients
TL;DR: This paper proposes a novel technique for developing a committee of classifiers aiming at supporting the decision making relative to inpatient respiratory isolation, and confirms that the resulting committees have outperformed several recently proposed single-models and ensemble solutions, including deep learning techniques.
Journal ArticleDOI
Assessing new strategies for TB diagnosis in low- and middle-income countries
Afrânio Lineu Kritski,Paula I. Fujiwara,M. A. Vieira,Antonio Ruffino Netto,Martha Maria Oliveira,Gisele Huf,Gisele Huf,S. Bertel Squire +7 more
TL;DR: The current situation of tuberculosis globally and in Brazil, the need for new strategies toward tuberculosis control, focusing on new diagnostic technologies is reported, and critical comments are given on the state of the art regarding the evaluation of new health technologies.