A
Agnieszka Gunia-Krzyżak
Researcher at Jagiellonian University Medical College
Publications - 34
Citations - 467
Agnieszka Gunia-Krzyżak is an academic researcher from Jagiellonian University Medical College. The author has contributed to research in topics: Chemistry & Anticonvulsant. The author has an hindex of 9, co-authored 29 publications receiving 311 citations. Previous affiliations of Agnieszka Gunia-Krzyżak include Jagiellonian University.
Papers
More filters
Journal ArticleDOI
Piperlongumine (piplartine) as a lead compound for anticancer agents - Synthesis and properties of analogues: A mini-review.
Kamil Piska,Agnieszka Gunia-Krzyżak,Paulina Koczurkiewicz,Katarzyna Wójcik-Pszczoła,Elżbieta Pękala +4 more
TL;DR: In this review, the synthesis of piperlongumine analogues and piper longumine-based hybrid compounds, as well as their anticancer properties and the molecular basis for their activity are explored.
Journal ArticleDOI
Cinnamic acid derivatives in cosmetics: current use and future prospects
Agnieszka Gunia-Krzyżak,Karolina Słoczyńska,Justyna Popiół,Paulina Koczurkiewicz,Henryk Marona,Elżbieta Pękala +5 more
TL;DR: Cinnamic acid derivatives, which is currently indexed as a skin‐conditioning cosmetics ingredient, has been widely tested in vitro and in vivo as a new drug candidate for the treatment of hyperpigmentation and may become new cosmetic ingredients in the future.
Journal ArticleDOI
Metabolic stability and its role in the discovery of new chemical entities
Karolina Słoczyńska,Agnieszka Gunia-Krzyżak,Paulina Koczurkiewicz,Katarzyna Wójcik-Pszczoła,Dorota Żelaszczyk,Justyna Popiół,Elżbieta Pękala +6 more
TL;DR: Issues of compound metabolic stability will be discussed, with special emphasis on its significance, in vitro metabolic stability testing, dilemmas regarding in vitro-in vivo extrapolation of the results and some aspects relating to different preclinical species used in in vivo metabolic stability assessment of compounds.
Journal ArticleDOI
Melanogenesis Inhibitors: Strategies for Searching for and Evaluation of Active Compounds
TL;DR: A review of melanogenesis inhibitors can be found in this paper, with a focus on utilization of various models for evaluation of mechanisms of action of tested compounds, and the potential limitations of the methods are also discussed.
Journal ArticleDOI
Cinnamamide Derivatives for Central and Peripheral Nervous System Disorders--A Review of Structure-Activity Relationships.
TL;DR: The literature data from reports evaluating cinnamic acid amide derivatives for activity in target‐based or phenotypic assays, both in vivo and in vitro, relevant to disorders of the central and peripheral nervous systems are analyzed and structure–activity relationships discussed.