H
Henryk Marona
Researcher at Jagiellonian University Medical College
Publications - 133
Citations - 1636
Henryk Marona is an academic researcher from Jagiellonian University Medical College. The author has contributed to research in topics: Xanthone & Anticonvulsant. The author has an hindex of 20, co-authored 128 publications receiving 1365 citations. Previous affiliations of Henryk Marona include Jagiellonian University.
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Journal ArticleDOI
Ion Channels as Drug Targets in Central Nervous System Disorders
Anna M. Waszkielewicz,Agnieszka Gunia,Natalia Szkaradek,Karolina Słoczyńska,S. Krupinska,Henryk Marona +5 more
TL;DR: This review is focusing on ion channels subtypes, which play a significant role in current drug discovery and development process, and new channels such as P2X1-P2X7, as well as TRPA1-TRPV1 have been discovered, giving premises for new types of analgesic drugs.
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Cinnamic acid derivatives in cosmetics: current use and future prospects
Agnieszka Gunia-Krzyżak,Karolina Słoczyńska,Justyna Popiół,Paulina Koczurkiewicz,Henryk Marona,Elżbieta Pękala +5 more
TL;DR: Cinnamic acid derivatives, which is currently indexed as a skin‐conditioning cosmetics ingredient, has been widely tested in vitro and in vivo as a new drug candidate for the treatment of hyperpigmentation and may become new cosmetic ingredients in the future.
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Evaluation of anticonvulsants for possible use in neuropathic pain.
TL;DR: This review is focusing on antiepileptic drugs, which are evaluated for their analgesic activity in major tests related with neuropathic pain, and examples are carbamazepine, gabapentin, and lacosamide as drugs well established in epilepsy market.
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Synthesis and evaluation of antidepressant-like activity of some 4-substituted 1-(2-methoxyphenyl)piperazine derivatives.
Anna M. Waszkielewicz,Karolina Pytka,Anna Rapacz,Elżbieta Wełna,Monika Jarzyna,Grzegorz Satała,Andrzej J. Bojarski,Jacek Sapa,Paweł Żmudzki,Barbara Filipek,Henryk Marona +10 more
TL;DR: A series of new derivatives of N‐(2‐methoxyphenyl)piperazine have been synthesized for their affinity toward serotonergic receptors and for their potential antidepressant‐like activity, with the most promising compound exhibiting affinity toward receptors Ki <1 nm (5‐HT1A) and Ki = 34 nm ( 5‐HT7).
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Melanogenesis Inhibitors: Strategies for Searching for and Evaluation of Active Compounds
TL;DR: A review of melanogenesis inhibitors can be found in this paper, with a focus on utilization of various models for evaluation of mechanisms of action of tested compounds, and the potential limitations of the methods are also discussed.