Ahitsham Umar

TL;DR: In this article, immunoinformatics approaches were employed to predict the antigenic epitopes against SARS-CoV-2 for the development of the coronavirus vaccine, and four CTL epitopes with antigenic sites were analyzed followed by binding affinity and binding interaction analyses of top-ranked predicted peptides with MHC-I HLA molecule.

TL;DR: A comprehensive study of natural compounds demonstrated with their anti-aging activities along with databases of natural products for drug designing was executed and summarized in this review article as mentioned in this paper, where the authors concluded that natural compounds are being utilized in drug design and development through computational and high throughput techniques for effective pro-longevity drugs.

TL;DR: Wang et al. as mentioned in this paper combined immunological approaches with molecular docking approaches for three highly antigenic proteins to design vaccines against Klebsiella aerogenes, and the synthesis of the B-cell, T-cell (CTL and HTL) and IFNγ epitopes of the targeted proteins was performed and most conserved epitopes were chosen for future research studies.

TL;DR: The multi-epitope-based vaccine (MEBV) was developed to aid in the prevention of L. pneumophila infections and to prove the MEBV's efficacy, more experimental validation is required.