Aja Greve

TL;DR: A comprehensive study of comorbidity within mental disorders is undertaken, by providing temporally ordered age- and sex-specific pairwise estimates between the major groups of mental disorders, and to develop an interactive website to visualize all results and guide future research and clinical practice.

TL;DR: It is hypothesized that a larger proportion of children growing up with an ill parent will display abnormal or delayed development, behavioural problems or psychiatric symptoms compared to the healthy controls.

TL;DR: Children with FHR-SZ had widespread neurocognitive impairments, supporting the hypothesis of neuroc cognitive functions as endophenotypes of schizophrenia, and the absence of Neurocognitive deficits in children with F HR-BP suggests distinct neurodevelopmental manifestations in these familial high-risk groups at this age.

TL;DR: Already at the age of seven, F HR‐SZ and FHR‐BP children show a higher prevalence of a broad spectrum of categorical and dimensional psychopathology compared with controls, emphasize the need for developing early intervention strategies towards this vulnerable group of children.

TL;DR: Motor abnormalities in children with a familial risk of schizophrenia are specific at 7 years of age with respect to fine motor function and balance, but non-specific with respectto familialrisk of bipolar disorder.