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Akio Wanaka
Researcher at Nara Medical University
Publications - 171
Citations - 7431
Akio Wanaka is an academic researcher from Nara Medical University. The author has contributed to research in topics: Gene expression & Embryonic stem cell. The author has an hindex of 47, co-authored 164 publications receiving 7024 citations. Previous affiliations of Akio Wanaka include Washington University in St. Louis & Fukushima Medical University.
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Journal ArticleDOI
Localization of bcl-2, bax, and bcl-x mRNAs in the developing inner ear of the mouse.
Nobuko Ishii,Akio Wanaka,Koji Ohno,Kazumasa Matsumoto,Yutaka Eguchi,Tetsuji Mori,Yoshihide Tsujimoto,Masaya Tohyama +7 more
TL;DR: The differential expression patterns in the cochleovestibular neurons suggest that proliferating and differentiating neurons utilize distinct members of the bcl-2 family in the differentiation of sensory epithelial cells, spiral ganglia, and stria vascularis.
Journal ArticleDOI
Hedgehog Signaling Modulates the Release of Gliotransmitters from Cultured Cerebellar Astrocytes
Hiroaki Okuda,Kouko Tatsumi,Shoko Morita-Takemura,Kazuki Nakahara,Katsunori Nochioka,Takeaki Shinjo,Yuki Terada,Akio Wanaka +7 more
TL;DR: The results suggested that the Hh signaling pathway sustains the release of glutamate and ATP and participates in neuro-glial interactions in the adult mouse brain and it is proposed that signaling pathways distinct from the HH pathway govern d-serine secretion from adult cerebellar astrocytes.
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A sequence-specific splicing activator, Tra2β, is up-regulated in response to nerve injury
TL;DR: This study could be the first observation showing that an expression of the sequence-specific splicing activator is enhanced in neuronal cells in response to nerve injury, and indicates that Tra2beta may participate in the control of injury- specific splicing patterns in order to express molecules which are necessary for regeneration.
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Differential Expression of Decorin and Biglycan Genes During Palatogenesis in Normal and Retinoic Acid-Treated Mice
Yuxiang Zhang,Tetsuji Mori,Ken Iseki,Seita Hagino,Hiromi Takaki,Mayumi Takeuchi,Tsuyoshi Hikake,Choichiro Tase,Masahiro Murakawa,Sachihiko Yokoya,Akio Wanaka +10 more
TL;DR: It is suggested that decorin and bigly can play distinct roles in palatogenesis, and decorin was more actively involved in the process of secondary palate formation than biglycan.
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Expression of hyperpolarization-activated cyclic nucleotide-gated cation channels in rat dorsal root ganglion neurons innervating urinary bladder.
Hiroko Matsuyoshi,Noriyuki Masuda,Michael B. Chancellor,Vickie L. Erickson,Yoshihiko Hirao,William C. de Groat,Akio Wanaka,Naoki Yoshimura +7 more
TL;DR: The results suggest that HCN-2 is the predominant subtype of HCN channels, which can control neuronal excitability, in small-sized C-fiber and medium-sized Adelta fiber DRG neurons including bladder afferent neurons, and might modulate activity of bladder Afferent pathways controlling the micturition reflex.