A
Akiteru Goto
Researcher at Akita University
Publications - 123
Citations - 4008
Akiteru Goto is an academic researcher from Akita University. The author has contributed to research in topics: Lung cancer & Adenocarcinoma. The author has an hindex of 33, co-authored 114 publications receiving 3484 citations. Previous affiliations of Akiteru Goto include Kyorin University & University of Tokyo.
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Journal ArticleDOI
MiR-21 is an EGFR-regulated anti-apoptotic factor in lung cancer in never-smokers
Masahiro Seike,Akiteru Goto,Tetsuya Okano,Tetsuya Okano,Elise D. Bowman,Aaron J. Schetter,Izumi Horikawa,Ewy Mathé,Jin Jen,Ping Yang,Haruhiko Sugimura,Akihiko Gemma,Shoji Kudoh,Carlo M. Croce,Curtis C. Harris +14 more
TL;DR: Aberrantly increased expression of miR-21, which is enhanced further by the activated EGFR signaling pathway, plays a significant role in lung carcinogenesis in never-smokers, as well as in smokers, and is a potential therapeutic target in both EGFR-mutant and wild-type cases.
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Molecular identification of a novel carnitine transporter specific to human testis. Insights into the mechanism of carnitine recognition.
Atsushi Enomoto,Michael F. Wempe,Hiroki Tsuchida,Ho Jung Shin,Seok Ho Cha,Naohiko Anzai,Akiteru Goto,Atsuhiko Sakamoto,Toshimitsu Niwa,Yoshikatsu Kanai,M. W. Anders,Hitoshi Endou +11 more
TL;DR: The identification of CT2 represents an interesting evolutionary link between OCT/OCTNs and OATs, as well as provides an important insight into the maturation of human spermatozoa.
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Matrilysin (MMP-7) as a significant determinant of malignant potential of early invasive colorectal carcinomas.
Tadahiko Masaki,Hiroyoshi Matsuoka,Masanori Sugiyama,N. Abe,Akiteru Goto,Atsuhiko Sakamoto,Yutaka Atomi +6 more
TL;DR: Tumour budding at the invasive margin and matrilysin expression are more useful in identifying high-risk groups for adverse outcome in patients with early invasive colorectal carcinomas.
Journal ArticleDOI
c-Met activation in lung adenocarcinoma tissues: An immunohistochemical analysis
Yu Nakamura,Toshiro Niki,Akiteru Goto,Teppei Morikawa,Keiji Miyazawa,Jun Nakajima,Masashi Fukayama +6 more
TL;DR: The data suggest that in lung adenocarcinoma tissue, c‐Met activation may take place either ligand‐dependently or ligand-independently via c‐ Met overexpression.
Journal ArticleDOI
MicroRNA Expression and Clinical Outcomes in Patients Treated with Adjuvant Chemotherapy after Complete Resection of Non–Small Cell Lung Carcinoma
Johannes Voortman,Akiteru Goto,Jean Mendiboure,Jane J. Sohn,Aaron J. Schetter,Motonobu Saito,Ariane Dunant,Trung C. Pham,Iacopo Petrini,Alan Lee,Mohammed A. Khan,Pierre Hainaut,Jean-Pierre Pignon,Elisabeth Brambilla,Helmut Popper,Martin Filipits,Curtis C. Harris,Giuseppe Giaccone +17 more
TL;DR: The results indicate that the microRNA expression patterns examined were neither predictive nor prognostic in a large patient cohort with radically resected NSCLC, randomized to receive adjuvant cisplatin-based chemotherapy versus follow-up only.