C
Curtis C. Harris
Researcher at National Institutes of Health
Publications - 655
Citations - 74644
Curtis C. Harris is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Carcinogenesis & Cancer. The author has an hindex of 130, co-authored 642 publications receiving 70671 citations. Previous affiliations of Curtis C. Harris include University of Maryland, Baltimore.
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Journal ArticleDOI
A microRNA expression signature of human solid tumors defines cancer gene targets
Stefano Volinia,George A. Calin,Chang Gong Liu,Stefan Ambs,Amelia Cimmino,Fabio Petrocca,Rosa Visone,Marilena V. Iorio,Claudia Roldo,Manuela Ferracin,Robyn L. Prueitt,Nozumu Yanaihara,Giovanni Lanza,Aldo Scarpa,Andrea Vecchione,Massimo Negrini,Curtis C. Harris,Carlo M. Croce +17 more
TL;DR: The results indicate that miRNAs are extensively involved in cancer pathogenesis of solid tumors and support their function as either dominant or recessive cancer genes.
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Unique microRNA molecular profiles in lung cancer diagnosis and prognosis
Nozomu Yanaihara,Natasha J. Caplen,Elise D. Bowman,Masahiro Seike,Kensuke Kumamoto,Ming Yi,Robert M. Stephens,Aikou Okamoto,Jun Yokota,Tadao Tanaka,George A. Calin,Chang Gong Liu,Carlo M. Croce,Curtis C. Harris +13 more
TL;DR: Results indicate that miRNA expression profiles are diagnostic and prognostic markers of lung cancer.
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MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma
Aaron J. Schetter,Suet Yi Leung,Jane J. Sohn,Krista A. Zanetti,Elise D. Bowman,Nozomu Yanaihara,Siu Tsan Yuen,Tsun Leung Chan,Dora L.W. Kwong,Gordon K.H. Au,Chang Gong Liu,George A. Calin,Carlo M. Croce,Curtis C. Harris +13 more
TL;DR: expression patterns of microRNAs are systematically altered in colon adenocarcinomas and high miR-21 expression is associated with poor survival and poor therapeutic outcome.
Journal ArticleDOI
Radical causes of cancer
TL;DR: Understanding the association between chronic inflammation and cancer provides insights into the molecular mechanisms involved and highlights the interaction between nitric oxide and p53 as a crucial pathway in inflammatory-mediated carcinogenesis.
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Clinical implications of the p53 tumor-suppressor gene
TL;DR: The p53 tumor-suppressor gene is the most striking example because it is mutated in about half of almost all types of cancer arising from a wide spectrum of tissues.