E
Elise D. Bowman
Researcher at National Institutes of Health
Publications - 114
Citations - 13439
Elise D. Bowman is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Lung cancer & Cancer. The author has an hindex of 52, co-authored 111 publications receiving 12639 citations. Previous affiliations of Elise D. Bowman include Pennsylvania State University.
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Journal ArticleDOI
Unique microRNA molecular profiles in lung cancer diagnosis and prognosis
Nozomu Yanaihara,Natasha J. Caplen,Elise D. Bowman,Masahiro Seike,Kensuke Kumamoto,Ming Yi,Robert M. Stephens,Aikou Okamoto,Jun Yokota,Tadao Tanaka,George A. Calin,Chang Gong Liu,Carlo M. Croce,Curtis C. Harris +13 more
TL;DR: Results indicate that miRNA expression profiles are diagnostic and prognostic markers of lung cancer.
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MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma
Aaron J. Schetter,Suet Yi Leung,Jane J. Sohn,Krista A. Zanetti,Elise D. Bowman,Nozomu Yanaihara,Siu Tsan Yuen,Tsun Leung Chan,Dora L.W. Kwong,Gordon K.H. Au,Chang Gong Liu,George A. Calin,Carlo M. Croce,Curtis C. Harris +13 more
TL;DR: expression patterns of microRNAs are systematically altered in colon adenocarcinomas and high miR-21 expression is associated with poor survival and poor therapeutic outcome.
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MiR-21 is an EGFR-regulated anti-apoptotic factor in lung cancer in never-smokers
Masahiro Seike,Akiteru Goto,Tetsuya Okano,Tetsuya Okano,Elise D. Bowman,Aaron J. Schetter,Izumi Horikawa,Ewy Mathé,Jin Jen,Ping Yang,Haruhiko Sugimura,Akihiko Gemma,Shoji Kudoh,Carlo M. Croce,Curtis C. Harris +14 more
TL;DR: Aberrantly increased expression of miR-21, which is enhanced further by the activated EGFR signaling pathway, plays a significant role in lung carcinogenesis in never-smokers, as well as in smokers, and is a potential therapeutic target in both EGFR-mutant and wild-type cases.
Journal Article
Manganese Superoxide Dismutase (MnSOD) Genetic Polymorphisms, Dietary Antioxidants, and Risk of Breast Cancer
Christine B. Ambrosone,Jo L. Freudenheim,Patricia A. Thompson,Elise D. Bowman,John E. Vena,James R. Marshall,Saxon Graham,Rosemary Laughlin,Takuma Nemoto,Peter G. Shields +9 more
TL;DR: The finding that risk was greatest among women who consumed lower amounts of dietary antioxidants and was minimal among high consumers indicates that a diet rich in sources of antioxidants may minimize the deleterious effects of the MnSOD polymorphism, thereby supporting public health recommendations for the consumption of diets rich in fruits and vegetables as a preventive measure against cancer.
Journal ArticleDOI
MicroRNA Expression in Squamous Cell Carcinoma and Adenocarcinoma of the Esophagus: Associations with Survival
Ewy Mathé,Giang Nguyen,Elise D. Bowman,Yiqiang Zhao,Yiqiang Zhao,Anuradha Budhu,Aaron J. Schetter,Rosemary Braun,Mark Reimers,Kensuke Kumamoto,Duncan B. Hughes,Nasser K. Altorki,Alan G. Casson,Chang Gong Liu,Xin Wei Wang,Nozomu Yanaihara,Nobutoshi Hagiwara,Andrew J. Dannenberg,Masao Miyashita,Carlo M. Croce,Curtis C. Harris +20 more
TL;DR: Evaluated miRNAs involved in major histologic types of esophageal carcinoma and uncover significant associations with prognosis were independent of tumor stage or nodal status, cohort type, and chemoradiation therapy.