A
Albert de la Chapelle
Researcher at Ohio State University
Publications - 421
Citations - 68531
Albert de la Chapelle is an academic researcher from Ohio State University. The author has contributed to research in topics: Gene & Cancer. The author has an hindex of 109, co-authored 421 publications receiving 63666 citations. Previous affiliations of Albert de la Chapelle include Merck & Co. & University of Ulm.
Papers
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Journal ArticleDOI
Prostate cancer incidence in males with Lynch syndrome.
Sigurdis Haraldsdottir,Heather Hampel,Lai Wei,Christina Wu,Tanios Bekaii-Saab,Albert de la Chapelle,Richard M. Goldberg +6 more
TL;DR: This retrospective study assesses whether the incidence of prostate cancer is increased above that of the general population in MMR mutation carriers in Lynch syndrome.
Journal ArticleDOI
Genetic Characterization and Prognostic Relevance of Acquired Uniparental Disomies in Cytogenetically Normal Acute Myeloid Leukemia.
Christopher J. Walker,Jessica Kohlschmidt,Ann-Kathrin Eisfeld,Krzysztof Mrózek,Sandya Liyanarachchi,Chi Song,Deedra Nicolet,James S. Blachly,Marius Bill,Dimitrios Papaioannou,Christopher C. Oakes,Brian Giacopelli,Luke K Genutis,Sophia E. Maharry,Shelley Orwick,Kellie J. Archer,Bayard L. Powell,Jonathan E. Kolitz,Geoffrey L. Uy,Eunice S. Wang,Andrew J. Carroll,Richard Stone,John C. Byrd,Albert de la Chapelle,Clara D. Bloomfield +24 more
TL;DR: In this paper, the frequency and prognostic significance of UPDs in patients with de novo acute myeloid leukemia (CN-AML) were examined. But, they did not examine the effect of the UPD on the outcome.
Journal ArticleDOI
Hemophilia A: genetic prediction and linkage studies in all available families in Finland.
TL;DR: RFLP segregation analysis provides a highly useful method of carrier detection and prenatal diagnosis of hemophilia A, but its limitations must be carefully taken into account.
Patent
Human MSH2 protein
TL;DR: The human MSH2 gene, responsible for hereditary non-polyposis colorectal cancer, was identified by virtue of its homology to the MutS class of genes, which are involved in DNA mismatch repair.
Journal ArticleDOI
Inherited Human Diseases: Victories, Challenges, Disappointments*
TL;DR: De la Cha-pelle et al. as discussed by the authors presented at the annual meeting of The AmericanSociety of Human Genetics, in Baltimore, on October 18, 2002, on the topic of "Human Cancer Genetics Program, 646 Tzagournis MedicalResearch Facility, 420 West 12th Avenue, Columbus, OH 43210".