Aldo Bigotti

TL;DR: The results show that while in normal, adult, human tissues total FN has a widespread distribution, the B-FN isoform is restricted only to synovial cells, to some vessels and areas of the interstitium of the ovary, and to the myometrium, and the results demonstrate that, in vivo, different FN isoforms have a differential distribution.

TL;DR: Results suggest that ICAM-1 may be a useful marker in the analysis of the molecular mechanism underlying the association between lesion thickness and clinical course of the disease.

TL;DR: The findings indicate that the expression of the p185 HER2 represents a tumor marker of clinical relevance in breast cancer, and whether this holds true for other malignancies remains to be explored.

TL;DR: Findings show that the c-MET gene is expressed at late stages of melanoma progression and suggest that the presence of Met/HGF receptor may contribute to the acquisition of an invasive phenotype.

TL;DR: The present results demonstrate that the c-kit receptor plays a role in the development of a larger spectrum of cell lineages, and speculate that, while in some cell types, c-Kit expression positively regulates mitogenesis and is selected for in neoplastic transformation, in other tissues thec-kit pathway is involved in morphogenesis and differentiation and is, therefore, negatively selected in the course of tumor progression.