A
Alessandra Di Masi
Researcher at Roma Tre University
Publications - 8
Citations - 114
Alessandra Di Masi is an academic researcher from Roma Tre University. The author has contributed to research in topics: DNA repair & DNA damage. The author has an hindex of 4, co-authored 8 publications receiving 81 citations. Previous affiliations of Alessandra Di Masi include University of Trieste.
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Structural Basis of Drug Recognition by Human Serum Albumin
TL;DR: The modulation of ligand binding to HSA is relevant not only under physiological conditions, but also in the pharmacological therapy management as several factors can modulate drug binding.
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The R215W mutation in NBS1 impairs γ-H2AX binding and affects DNA repair: molecular bases for the severe phenotype of 657del5/R215W Nijmegen breakage syndrome patients
Alessandra Di Masi,Mara Viganotti,Fabio Polticelli,Paolo Ascenzi,Caterina Tanzarella,Antonio Antoccia +5 more
TL;DR: It is demonstrated that the R215W mutation in NBS1 impairs histone gamma-H2AX binding after induction of DNA damage, leading to a delay in DNA-DSB rejoining, and could explain the severe phenotype observed in 657del5/R215W NBS patients.
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Targeting the DNA Double Strand Breaks Repair for Cancer Therapy
TL;DR: An overview about D SBs damage response is provided, focusing on the role of the DSBs repair mechanisms, of chromatin modifications, and of the cancer susceptibility gene BRCA1 which plays a multifunctional role in controlling genome integrity.
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Biocompatibility and antibacterial properties of TiCu(Ag) thin films produced by physical vapor deposition magnetron sputtering
Saqib Rashid,Gian Marco Vita,Luca Persichetti,Giovanna Iucci,Chiara Battocchio,Rostislav Daniel,Daniela Visaggio,Martina Marsotto,Paolo Visca,Edoardo Bemporad,Paolo Ascenzi,Paolo Ascenzi,Giovanni Capellini,Marco Sebastiani,Alessandra Di Masi +14 more
TL;DR: In this paper, the authors investigated the link existing between structural and functional properties of TiCu(Ag) thin films deposited by physical vapor deposition magnetron sputtering (MS-PVD) on Si substrates.
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Xenosensors CAR and PXR at Work: Impact on Statin Metabolism
Maria Marino,Alessandra Di Masi,Viviana Trezza,Valentina Pallottini,Fabio Polticelli,Paolo Ascenzi +5 more
TL;DR: The structural and molecular bases of CAR- and PXR-mediated drug response highlighting how these mechanisms could impact on statin metabolism and the alteration of statin pharmacodynamics and/or pharmacokinetics induced by concomitant drug treatment or dietary factors are reviewed.