Alessandro Serretti

TL;DR: Results show that AAs may have a beneficial effect in the treatment of PTSD, as indicated by the changes from baseline in Clinician Administered PTSD Scale total scores, and clinical significance of the results should be carefully interpreted and translated into clinical practice.

TL;DR: The state-of-the-art methodology is reviewed, the use of a range of response criteria and the inclusion of possible environmental confounding variables are suggested as possible guideline for future studies.

TL;DR: Clinical studies demonstrate that aripiprazole may be useful in the treatment of bipolar depression, major depressive disorder, treatment-resistant depression and possibly anxiety disorders, and available evidence from randomized, placebo-controlled trials is sparse, and a formal risk/benefit assessment of the use of these agents in a nonpsychotic patient population is not yet possible.

TL;DR: In this paper, the possible influence of a set of candidate genes as genetic predictors of AD response efficacy was investigated by us and others, including the cytochrome P450 (CYP) superfamily, the P-glycoprotein (ABCB1), the tryptophan hydroxylase (TPH), the catechol-O-methyltransferase (COMT), the monoamine oxidase A (MAOA), the serotonin transporter (5-HTTLPR), the norepinephrine transporter (NET), the dopamine transporter (DAT

TL;DR: In this article, the authors investigated the possible association between the tryptophan hydroxylase (TPH) gene and prophylactic efficacy of lithium in mood disorders.