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Alessandro Serretti

Researcher at University of Bologna

Publications -  817
Citations -  35088

Alessandro Serretti is an academic researcher from University of Bologna. The author has contributed to research in topics: Bipolar disorder & Major depressive disorder. The author has an hindex of 81, co-authored 711 publications receiving 30197 citations. Previous affiliations of Alessandro Serretti include University of Sassari & Vita-Salute San Raffaele University.

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Clinical characteristics and treatment outcomes of patients with major depressive disorder and comorbid anxiety disorders - results from a European multicenter study.

TL;DR: The findings suggest that the various anxiety disorders subtypes display divergent clinical characteristics and are associated with different variables, especially comorbid GAD appears to be characterized by high symptom severity and poor treatment response.
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The combined effect of genetic polymorphisms and clinical parameters on treatment outcome in treatment-resistant depression.

TL;DR: The random forests prediction model for treatment outcome showed that combining clinical and genetic variables gradually increased the prediction performance recognizing correctly 25% of responders using all 4 factors, and furthermore shows the strength of an interaction-based model combining statistical algorithms in identifying and operating treatment predictors.
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Further evidence of a combined effect of SERTPR and TPH on SSRIs response in mood disorders.

TL;DR: The present independent replication confirms SERTPR variants as a liability factor for antidepressant efficacy while the TPH effect is not unequivocal.
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Novel antipsychotics specificity profile: A clinically oriented review of lurasidone, brexpiprazole, cariprazine and lumateperone.

TL;DR: These new antipsychotics were developed with the aim of improving efficacy on negative and depressive symptoms and reducing metabolic and cardiovascular side effects compared to prior SGAs, while keeping the risk of extrapyramidal symptoms low.
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Opiate detoxification of methadone maintenance patients using lefetamine, clonidine and buprenorphine

TL;DR: It was shown that tapering methadone to low doses before entering the pharmacologically assisted discontinuation phase was clinically acceptable in detoxification from long-term methadon treatment.