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Alex Kong
Researcher at Stanford University
Publications - 4
Citations - 202
Alex Kong is an academic researcher from Stanford University. The author has contributed to research in topics: Cell morphology & Segmentation. The author has an hindex of 3, co-authored 4 publications receiving 36 citations.
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Journal ArticleDOI
Whole-cell segmentation of tissue images with human-level performance using large-scale data annotation and deep learning.
Noah F. Greenwald,Geneva Miller,Erick Moen,Alex Kong,Adam Kagel,Thomas Dougherty,Christine Camacho Fullaway,Brianna J. McIntosh,Ke Xuan Leow,Morgan Schwartz,Cole Pavelchek,Cole Pavelchek,Sunny Cui,Sunny Cui,Isabella Camplisson,Omer Bar-Tal,Jaiveer Singh,Mara Fong,Mara Fong,Gautam Chaudhry,Zion Abraham,Jackson Moseley,Shiri Warshawsky,Erin Soon,Shirley Greenbaum,Tyler Risom,Travis J. Hollmann,Sean C. Bendall,Leeat Keren,William Graf,Michael Angelo,David Van Valen +31 more
TL;DR: TissueNet as mentioned in this paper is a dataset for training segmentation models that contains more than 1 million manually labeled cells, an order of magnitude more than all previously published segmentation training datasets.
Posted ContentDOI
Whole-cell segmentation of tissue images with human-level performance using large-scale data annotation and deep learning
Noah F. Greenwald,Geneva Miller,Erick Moen,Alex Kong,Adam Kagel,Christine Camacho Fullaway,Brianna J. McIntosh,Ke Leow,Morgan Schwartz,Thomas Dougherty,Cole Pavelchek,Cole Pavelchek,Sunny Cui,Sunny Cui,Isabella Camplisson,Omer Bar-Tal,Jaiveer Singh,Mara Fong,Gautam Chaudhry,Zion Abraham,Jackson Moseley,Shiri Warshawsky,Erin Soon,Shirley Greenbaum,Tyler Risom,Travis J. Hollmann,Leeat Keren,William Graf,Michael Angelo,David Van Valen +29 more
TL;DR: Mesmer as mentioned in this paper is a deep learning-enabled segmentation algorithm trained on TissueNet that performs nuclear and whole-cell segmentation in tissue imaging data, which can be adapted to harness cell lineage information present in highly multiplexed datasets.
Posted ContentDOI
Transition to invasive breast cancer is associated with progressive changes in the structure and composition of tumor stroma
Tyler Risom,David R. Glass,Candace C. Liu,Belén Rivero-Gutiérrez,Alex Baranski,Erin McCaffrey,Noah F. Greenwald,Adam Kagel,Siri H Strand,Sushama Varma,Alex Kong,Leeat Keren,Sucheta Srivastava,Chunfang Zhu,Zumana Khair,Deborah J. Veis,Katherine DeSchryver,Sujay Vennam,Carlo C. Maley,E. Shelley Hwang,Jefferey R Marks,Sean C. Bendall,Graham A. Colditz,Robert B. West,Michael Angelo +24 more
TL;DR: In this paper, the transition from DCIS to IBC was found to occur along a trajectory marked by coordinated shifts in location and function of myoepithelium, fibroblasts, and infiltrating immune cells in the surrounding stroma.
Posted ContentDOI
Reproducible, high-dimensional imaging in archival human tissue by Multiplexed Ion Beam Imaging by Time-of-Flight (MIBI-TOF)
Candace C. Liu,Marc Bosse,Alex Kong,Adam Kagel,Robert J. Kinders,Stephen M. Hewitt,Sean C. Bendall,Michael Angelo +7 more
TL;DR: In this paper, the authors conducted a validation study, assessing concordance across a dozen serial sections of a tissue microarray of 21 samples that were independently processed and imaged by MIBI-TOF or single-plex immunohistochemistry (IHC) over 12 days.