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Alexander Liede
Researcher at Amgen
Publications - 87
Citations - 3354
Alexander Liede is an academic researcher from Amgen. The author has contributed to research in topics: Breast cancer & Population. The author has an hindex of 27, co-authored 81 publications receiving 2914 citations. Previous affiliations of Alexander Liede include Women's College, Kolkata & National Institutes of Health.
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Journal ArticleDOI
Cancer Risks for Male Carriers of Germline Mutations in BRCA1 or BRCA2: A Review of the Literature
TL;DR: This article reviews studies that estimate risk associated with mutations in BRCA1 or BRCa2, with a focus on the cancer sites most relevant to men, to determine the magnitude of excess cancer risk among BRC a2 carriers and to increase the understanding of the basis for the observed site-specificity in cancer development.
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Prevalence and Penetrance of BRCA1 and BRCA2 Gene Mutations in Unselected Ashkenazi Jewish Women With Breast Cancer
Ellen Warner,William D. Foulkes,Pamela J. Goodwin,Wendy S. Meschino,John Blondal,Colleen Paterson,Hilmi Ozcelik,Paul E. Goss,Diane Allingham-Hawkins,Nancy Hamel,Lisa Di Prospero,Velita Contiga,Corinne Serruya,Meri Klein,Roxana Moslehi,Joanne Honeyford,Alexander Liede,Gordon Glendon,Jean-Sébastien Brunet,Steven A. Narod +19 more
TL;DR: Genetic testing may be useful when Jewish women with breast cancer are diagnosed before age 50 years or have a close relative with ovarian or early-onset breast cancer.
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Incidence of bone metastases in patients with solid tumors: analysis of oncology electronic medical records in the United States
TL;DR: These estimates of bone metastasis incidence represent the experience of a population with longer follow-up than previously published, and represent experience in the recent treatment landscape.
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Contribution of BRCA1 and BRCA2 mutations to breast and ovarian cancer in Pakistan
Alexander Liede,Alexander Liede,Imtiaz A. Malik,Zeba Aziz,Patricia de los Rios,Elaine Kwan,Steven A. Narod +6 more
TL;DR: The results suggest that recessively inherited genes may contribute to breast and ovarian cancer risk in Pakistan.
Journal ArticleDOI
Effect of Smoking on Breast Cancer in Carriers of Mutant BRCA1 or BRCA2 Genes
Jean Sébastien Brunet,Parviz Ghadirian,Timothy R. Rebbeck,Caryn Lerman,Judy Garber,Patricia N. Tonin,John Abrahamson,William D. Foulkes,Mary B. Daly,Josephine Wagner-Costalas,Andrew K. Godwin,Olufunmilayo I. Olopade,Roxana Moslehi,Alexander Liede,P. Andrew Futreal,Barbara L. Weber,Gilbert M. Lenoir,Henry T. Lynch,Steven A. Narod +18 more
TL;DR: A matched case-control study of breast cancer among women who have been identified to be carriers of a deleterious mutation in either the BRCA1 or theBRCA2 gene raises the possibility that smoking reduces the risk of Breast cancer in carriers of BRC a1 or BRCa2 gene mutations.