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Alexander V. Kabanov
Researcher at University of North Carolina at Chapel Hill
Publications - 467
Citations - 38933
Alexander V. Kabanov is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Micelle & Drug delivery. The author has an hindex of 99, co-authored 447 publications receiving 34519 citations. Previous affiliations of Alexander V. Kabanov include McGill University & Tambov State University.
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Endocytosis of Nanomedicines
TL;DR: This review describes the current experimental tools to study endocytosis of nanomedicines and provides specific examples from recent literature and the authors' own work on endocyTosis of Nanomedicine.
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Pluronic® block copolymers as novel polymer therapeutics for drug and gene delivery
TL;DR: The interactions of the Pluronic unimers with multidrug-resistant cancer cells result in sensitization of these cells with respect to various anticancer agents and the single molecular chains of copolymer, unimers, inhibit drug efflux transporters in both the blood-brain barrier and in the small intestine.
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Exosomes as drug delivery vehicles for Parkinson's disease therapy.
Matthew J. Haney,Natalia L. Klyachko,Yuling Zhao,Richa Gupta,Evgeniya G. Plotnikova,Zhijian He,Tejash Patel,Aleksandr Piroyan,Marina Sokolsky,Alexander V. Kabanov,Elena V. Batrakova +10 more
TL;DR: ExoCAT provided significant neuroprotective effects in in vitro and in vivo models of PD and has a potential to be a versatile strategy to treat inflammatory and neurodegenerative disorders.
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Pluronic block copolymers: evolution of drug delivery concept from inert nanocarriers to biological response modifiers.
TL;DR: These studies suggest that Pluronics have a broad spectrum of biological response modifying activities which make it one of the most potent drug targeting systems available, resulting in a remarkable impact on the emergent field of nanomedicine.
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Nanogels as pharmaceutical carriers: finite networks of infinite capabilities.
TL;DR: This work has shown that polyelectrolyte nanogels can readily incorporate oppositely charged low-molecular-mass drugs and biomacromolecules such as oligo- and polynucleotides (siRNA, DNA) as well as proteins.