A
Alexandre Gaymard
Researcher at Claude Bernard University Lyon 1
Publications - 57
Citations - 3443
Alexandre Gaymard is an academic researcher from Claude Bernard University Lyon 1. The author has contributed to research in topics: Medicine & Viral load. The author has an hindex of 16, co-authored 40 publications receiving 2169 citations. Previous affiliations of Alexandre Gaymard include French Institute of Health and Medical Research & Northern Hospital.
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Journal ArticleDOI
Clinical and virological data of the first cases of COVID-19 in Europe: a case series.
François-Xavier Lescure,François-Xavier Lescure,Lila Bouadma,Lila Bouadma,Duc Bao Nguyen,Marion Parisey,Paul-Henri Wicky,Paul-Henri Wicky,Sylvie Behillil,Alexandre Gaymard,M. Bouscambert-Duchamp,Flora Donati,Quentin Le Hingrat,Quentin Le Hingrat,Vincent Enouf,Nadhira Houhou-Fidouh,M. Valette,Alexandra Mailles,Jean-Christophe Lucet,Jean-Christophe Lucet,Xavier Duval,Xavier Duval,Diane Descamps,Diane Descamps,Denis Malvy,Jean-François Timsit,Jean-François Timsit,Bruno Lina,Sylvie van-der-Werf,Yazdan Yazdanpanah,Yazdan Yazdanpanah +30 more
TL;DR: The relevant features of the first cases in Europe of confirmed infection, named coronavirus disease 2019 (COVID-19), with the first patient diagnosed with the disease on Jan 24, 2020, are reported and will contribute to advances in the implementation of more efficient infection control strategies.
Journal ArticleDOI
First cases of coronavirus disease 2019 (COVID-19) in the WHO European Region, 24 January to 21 February 2020
Gianfranco Spiteri,James E Fielding,Michaela Diercke,C Campese,Vincent Enouf,Alexandre Gaymard,Antonino Bella,Paola Sognamiglio,María José Sierra Moros,Antonio Nicolau Riutort,Yulia V. Demina,Romain Mahieu,Markku Broas,Malin Bengnér,Silke Buda,Julia Schilling,Laurent Filleul,Agnes Lepoutre,C. Saura,Alexandra Mailles,Daniel Lévy-Bruhl,Bruno Coignard,Sibylle Bernard-Stoecklin,Sylvie Behillil,Sylvie van der Werf,Martine Valette,Bruno Lina,Flavia Riccardo,Emanuele Nicastri,Inmaculada Casas,Amparo Larrauri,Magdalena Salom Castell,Francisco Pozo,Rinat A. Maksyutov,Charlotte Martin,Marc Van Ranst,Nathalie Bossuyt,Lotta Siira,Jussi Sane,Karin Tegmark-Wisell,Maria Palmérus,Eeva Broberg,Julien Beauté,Pernille Jorgensen,Nick Bundle,Dmitriy Pereyaslov,Cornelia Adlhoch,Jukka Pukkila,Richard Pebody,Sonja J. Olsen,Bruno Christian Ciancio +50 more
TL;DR: In the WHO European Region, COVID-19 surveillance was implemented 27 January 2020, and the first European cases are detailed, with among 38 cases studied, 21 were linked to two clusters in Germany and France, 14 were infected in China.
Journal ArticleDOI
Cluster of Coronavirus Disease 2019 (COVID-19) in the French Alps, February 2020.
Kostas Danis,Olivier Epaulard,Olivier Epaulard,Thomas Bénet,Alexandre Gaymard,Séphora Campoy,Elisabeth Botelho-Nevers,Maude Bouscambert-Duchamp,Guillaume Spaccaferri,Florence Ader,Alexandra Mailles,Zoubida Boudalaa,Violaine Tolsma,Julien Berra,Sophie Vaux,Emmanuel Forestier,Caroline Landelle,Caroline Landelle,Erica Fougere,Alexandra Thabuis,Philippe Berthelot,Raphael Veil,Daniel Lévy-Bruhl,Christian Chidiac,Bruno Lina,Bruno Coignard,C. Saura +26 more
TL;DR: The occurrence in this cluster of one asymptomatic case with similar viral load as a symptomatic patient, suggests transmission potential of asymPTomatic individuals and underscores the need for close monitoring of the clinical evolution of suspect Covid-19 cases.
Journal ArticleDOI
Type I IFN immunoprofiling in COVID-19 patients.
Sophie Trouillet-Assant,Sophie Trouillet-Assant,Sébastien Viel,Alexandre Gaymard,Sylvie Pons,Jean-Christophe Richard,Magali Perret,Marine Villard,Karen Brengel-Pesce,Bruno Lina,Mehdi Mezidi,Laurent Bitker,Alexandre Belot,William Mouton,Guy Oriol,Christelle Compagnon,Laurence Generenaz,Valérie Cheynet,Florence Ader,Agathe Becker,Nicholas Benech,Pierre Chauvelot,Christian Chidiac,Anne Conrad,Tristan Ferry,Patrick Miailhes,Thomas Perpoint,Marielle Perry,Cécile Pouderoux,Sandrine Roux,Claire Triffault-Fillit,Florent Valour,Yonis Hodane,Louis Chauvelot,Paul Chabert,Judith Provoost,Guillaume David,Laure Folliet,Pierre Lecam,Geneviève Billaud,Maude Bouscambert,Vanessa Escuret,Emilie Frobert,Antonin Bal,Grégory Destras,Laurence Josset,Florence Morfin,Clément Munier,Martine Valette,Fabienne Venet,Lorna Garnier,Rémi Pescarmona,Christine Lombard,Thierry Walzer +53 more
TL;DR: Immunoprofiling reveals heterogeneous IFN-α2 production with about 20% of critically-ill patients unable to produceIFN- α2, highlighting the immune response heterogeneity and opening avenues for targeted therapies.
Journal ArticleDOI
Remdesivir plus standard of care versus standard of care alone for the treatment of patients admitted to hospital with COVID-19 (DisCoVeRy): a phase 3, randomised, controlled, open-label trial.
Florence Ader,M. Bouscambert-Duchamp,Maya Hites,Nathan Peiffer-Smadja,Nathan Peiffer-Smadja,Julien Poissy,Drifa Belhadi,Alpha Diallo,Minh-Patrick Le,Gilles Peytavin,Thérèse Staub,Richard Greil,Jeremie Guedj,José Artur Paiva,Dominique Costagliola,Yazdan Yazdanpanah,Charles Burdet,Alexander Egle,Michael Joannidis,Bernd Lamprecht,Antoine Altdorfer,Leila Belkhir,Vincent Fraipont,Gil Verschelden,Jérôme Aboab,Hafid Ait-Oufella,Claire Andrejak,Pascal Andreu,Laurent Argaud,Firouzé Bani-Sadr,François Bénézit,M. Blot,Elisabeth Botelho-Nevers,Lila Bouadma,Olivier Bouchaud,David Bougon,Kevin Bouiller,Fanny Bounes-Vardon,David Boutoille,Alexandre Boyer,Cédric Bruel,André Cabié,Emmanuel Canet,Charles Cazanave,Cyrille Chabartier,Catherine Chirouze,Raphaël Clere-Jehl,Johan Courjon,Flora Crockett,François Danion,Agathe Delbove,Jean Dellamonica,F. Djossou,Clément Dubost,Alexandre Duvignaud,Olivier Epaulard,Loïc Epelboin,Murielle Fartoukh,Karine Faure,Emmanuel Faure,Tristan Ferry,Cécile Ficko,Samy Figueiredo,Benjamin Gaborit,Rostane Gaci,Amandine Gagneux-Brunon,Sébastien Gallien,Denis Garot,Guillaume Geri,Sébastien Gibot,François Goehringer,Marie Gousseff,Didier Gruson,Yves Hansmann,Olivier Hinschberger,Stéphane Jauréguiberry,Vanessa Jeanmichel,Solen Kernéis,Antoine Kimmoun,Kada Klouche,Marie Lachâtre,Karine Lacombe,Fabrice Laine,Jean-Philippe Lanoix,Odile Launay,Bruno Laviolle,Vincent Le Moing,Jérôme Le Pavec,Yves Le Tulzo,Paul Le Turnier,David Lebeaux,Benjamin Lefevre,Sylvie Leroy,François-Xavier Lescure,Henry Lessire,Benjamin Leveau,Paul Loubet,Alain Makinson,Denis Malvy,Charles-Hugo Marquette,Guillaume Martin-Blondel,Martin Martinot,Julien Mayaux,Armand Mekontso-Dessap,Ferhat Meziani,Jean-Paul Mira,Jean-Michel Molina,Xavier Monnet,Joy Mootien,Bruno Mourvillier,Marlène Murris-Espin,Jean-Christophe Navellou,Saad Nseir,Walid Oulehri,Thomas Perpoint,Gilles Pialoux,Benoit Pilmis,Vincent Piriou,Lionel Piroth,Valérie Pourcher,Jean-Pierre Quenot,François Raffi,Jean Reignier,Matthieu Revest,Jean-Christophe Richard,Béatrice Riu-Poulenc,Céline Robert,Pierre-Alexandre Roger,Claire Roger,Elisabeth Rouveix-Nordon,Yvon Ruch,Nadia Saidani,Naomi Sayre,Eric Senneville,Albert Sotto,Francois Stefan,Charles Tacquard,Nicolas Terzi,Julien Textoris,Guillaume Thiery,Jean-François Timsit,Violaine Tolsma,Jean-Marie Turmel,Florent Valour,Florent Wallet,Guilhem Wattecamps,Yoann Zerbib,Marc Berna,Jean Reuter,Sandra Braz,Joao-Miguel Ferreira Ribeiro,Roberto Roncon-Albuquerque,Alexandre Gaymard,Bruno Lina,Sarah Tubiana,Sandrine Couffin-Cadiergues,Hélène Espérou,Aline Dechanet,Christelle Delmas,Claire Fougerou,Noémie Mercier,Marion Noret,Juliette Saillard,Priyanka Velou +163 more
TL;DR: The DisCoVeRy trial as mentioned in this paper evaluated the clinical efficacy of remdesivir plus standard care compared with standard of care alone in patients admitted to hospital with COVID-19, with indication of oxygen or ventilator support.