F
Fabienne Venet
Researcher at Claude Bernard University Lyon 1
Publications - 229
Citations - 9269
Fabienne Venet is an academic researcher from Claude Bernard University Lyon 1. The author has contributed to research in topics: Septic shock & Sepsis. The author has an hindex of 40, co-authored 189 publications receiving 6831 citations. Previous affiliations of Fabienne Venet include Rhode Island Hospital & HCL Technologies.
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Journal ArticleDOI
Persisting low monocyte human leukocyte antigen-DR expression predicts mortality in septic shock
Guillaume Monneret,Alain Lepape,Nicolas Voirin,Julien Bohé,Fabienne Venet,Anne-Lise Debard,Hélène Thizy,Jacques Bienvenu,François Gueyffier,Philippe Vanhems +9 more
TL;DR: The present preliminary results show that mHLA-DR is an independent predictor of mortality in septic shock patients, and may help to stratify patients when designing a mediator-directed therapy in a time-dependent manner.
Journal ArticleDOI
PD-1 expression by macrophages plays a pathologic role in altering microbial clearance and the innate inflammatory response to sepsis
Xin Huang,Fabienne Venet,Yvonne L. Wang,Alain Lepape,Zhenglong Yuan,Yaping Chen,Ryan Swan,Hakim Kherouf,Guillaume Monneret,Chun-Shiang Chung,Alfred Ayala +10 more
TL;DR: Data suggest that PD-1 may not only be a dysfunctional marker/effector of macrophages/monocytes, but may also be a potential therapeutic target for designing measures to modulate the innate immune response, thereby preventing the detrimental effects of sepsis.
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Advances in the understanding and treatment of sepsis-induced immunosuppression
TL;DR: The reappraisal of sepsis pathophysiology has resulted in a novel approach to the design of clinical trials evaluating sepsi treatments, based on an evaluation of the immune status and biomarker-based stratification of patients.
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The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity.
Marcin F. Osuchowski,Martin Sebastian Winkler,Tomasz Skirecki,Sara Cajander,Manu Shankar-Hari,Manu Shankar-Hari,Gunnar Lachmann,Guillaume Monneret,Fabienne Venet,Michael Bauer,Frank M. Brunkhorst,Sebastian Weis,Alberto García-Salido,Matthijs Kox,Jean-Marc Cavaillon,Florian Uhle,Markus A. Weigand,Stefanie B. Flohé,W. Joost Wiersinga,Raquel Almansa,Amanda de la Fuente,Ignacio Martin-Loeches,Christian Meisel,Thibaud Spinetti,Joerg C. Schefold,Catia Cilloniz,Antoni Torres,Antoni Torres,Evangelos J. Giamarellos-Bourboulis,Ricard Ferrer,Ricard Ferrer,Massimo Girardis,Andrea Cossarizza,Mihai G. Netea,Mihai G. Netea,Mihai G. Netea,Tom van der Poll,Jesus F. Bermejo-Martin,Ignacio Rubio +38 more
TL;DR: The authors reviewed the intricacies of COVID-19 pathophysiology, its various phenotypes, and the anti-SARS-CoV-2 host response at the humoral and cellular levels.
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Monitoring immune dysfunctions in the septic patient: a new skin for the old ceremony.
TL;DR: This review focuses on immune dysfunctions described in septic patients and on their potential use as markers on a routine standardized basis for prediction of adverse outcome or of occurrence of secondary nosocomial infections.