K
Karine Lacombe
Researcher at University of Paris
Publications - 316
Citations - 5997
Karine Lacombe is an academic researcher from University of Paris. The author has contributed to research in topics: Medicine & Hepatitis B virus. The author has an hindex of 36, co-authored 240 publications receiving 4406 citations. Previous affiliations of Karine Lacombe include Pierre-and-Marie-Curie University & French Institute of Health and Medical Research.
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Journal ArticleDOI
Towards an HBV cure: state-of-the-art and unresolved questions—report of the ANRS workshop on HBV cure
Mirjam B. Zeisel,Julie Lucifora,William S. Mason,Camille Sureau,Jürgen Beck,Massimo Levrero,Michael Kann,Percy A. Knolle,Monsef Benkirane,David Durantel,Marie Michel,Brigitte Autran,François-Loïc Cosset,Helene Strick-Marchand,Christian Trepo,Jia-Horng Kao,Fabrice Carrat,Karine Lacombe,Raymond F. Schinazi,Françoise Barré-Sinoussi,Jean François Delfraissy,Fabien Zoulim +21 more
TL;DR: This review summarises the current understanding of HBV host-interactions leading to viral persistence, as well as the roadblocks to be overcome to ultimately address unmet medical needs in the treatment of chronic HBV infection.
Journal ArticleDOI
Convalescent plasma therapy for B-cell-depleted patients with protracted COVID-19.
Thomas Hueso,Thomas Hueso,Cécile Pouderoux,Hélène Péré,Anne Lise Beaumont,Laure Anne Raillon,Florence Ader,Lucienne Chatenoud,Deborah Eshagh,Tali Anne Szwebel,Martin Martinot,Fabrice Camou,Etienne Crickx,Marc Michel,Matthieu Mahévas,David Boutboul,David Boutboul,Elie Azoulay,Adrien Joseph,Olivier Hermine,Claire Rouzaud,Stanislas Faguer,Philippe Petua,Fanny Pommeret,Sébastien Clerc,Benjamin Planquette,Fatiha Merabet,Jonathan London,Valérie Zeller,David Ghez,David Veyer,Amani Ouedrani,Pierre Gallian,Jérôme Pacanowski,Arsène Mekinian,Marc Garnier,Pierre Tiberghien,Karine Lacombe +37 more
TL;DR: Convalescent plasma with anti–SARS-CoV-2 antibodies appears to be a very promising approach in the context of protracted COVID-19 symptoms in patients unable to mount a specific humoral response to SARS- CoV- 2.
Journal ArticleDOI
Effect of anakinra versus usual care in adults in hospital with COVID-19 and mild-to-moderate pneumonia (CORIMUNO-ANA-1): a randomised controlled trial
Pierre-Louis Tharaux,Gilles Pialoux,Arthur Pavot,Xavier Mariette,Olivier Hermine,Matthieu Resche-Rigon,Raphaël Porcher,Philippe Ravaud,Serge Bureau,Maxime Dougados,Annick Tibi,Elie Azoulay,Jacques Cadranel,Joseph Emmerich,Muriel Fartoukh,Bertrand Guidet,Marc Humbert,Karine Lacombe,Matthieu Mahévas,Frédéric Pène,Valérie Pourchet-Martinez,Frédéric Schlemmer,Yazdan Yazdanpanah,Gabriel Baron,Elodie Perrodeau,Damien Vanhoye,Cécile Kedzia,Lauren Demerville,Anne Gysembergh-Houal,Alexandre Bourgoin,Sarah Dalibey,Nabil Raked,Lakhdar Mameri,Stéphanie Alary,Samir Hamiria,Thinhinane Bariz,Hala Semri,Dhiaa Meriem Hai,Moustafa Benafla,Mohamed Belloul,Pernelle Vauboin,Saskia Flamand,Claire Pacheco,Anouk Walter-Petrich,Emilia Stan,Souad Benarab,Corine Nyanou,Claire Montlahuc,Lucie Biard,Robin Charreteur,Celine Dupré,Kévin Cardet,Blandine Lehmann,Kamyl Baghli,Claire Madelaine,Eric D'Ortenzio,Oriane Puéchal,Caroline Semaille,Laurent Savale,Anatole Harrois,Samy Figueiredo,Jacques Duranteau,Nadia Anguel,Xavier Monnet,Christian Richard,Jean-Louis Teboul,Philippe Durand,Pierre Tissieres,Mitja Jevnikar,David Montani,Sophie Bulifon,Xavier Jaïs,Olivier Sitbon,Stéphan Pavy,Nicolas Noel,Olivier Lambotte,Lelia Escaut,Stéphane Jauréguiberry,Elodie Baudry,Christiane Verny,Mathilde Noaillon,Edouard Lefèvre,Mohamad Zaidan,Clotilde Le Tiec Le Tiec,Céline Verstuyft Verstuyft,Anne-Marie Roques,Lamiae Grimaldi,Domitille Molinari,Gaël Leprun,Alain Fourreau,Laurent Cylly,Myriam Virlouvet,Ramdane Meftali,Solène Fabre,Marion Licois,Asmaa Mamoune,Yacine Boudali,Sophie Georgin-Lavialle,Patricia Senet,A Soria,Antoine Parrot,Hélène François,Nathalie Rozensztajn,Emmanuelle Blin,Pascaline Choinier,Juliette Camuset,Jean-Simon Rech,Antony Canellas,Camille Rolland-Debord,Nadège Lemarié,Nicolas Belaube,Marine Nadal,Martin Siguier,Camille Petit-Hoang,Julie Chas,Elodie Drouet,Matthieu Lemoine,Audrey Phibel,Lucie Aunay,Eliane Bertrand,Sylviane Ravato,Marie Vayssettes,Anne Adda,Celine Wilpotte,Pélagie Thibaut,Julie Fillon,Isabelle Debrix,Soraya Fellahi,Jean-Philippe Bastard,Guillaume Lefèvre,Vincent Fallet,Jacques-Eric Gottenberg,Yves Hansmann,Emmanuel Andrès,Sophie Bayer,Guillaume Becker,Frédéric Blanc,Stéphane Brin,Vincent Castelain,Emmanuel Chatelus,Eva Chatron,Olivier Collange,François Danion,Frédéric De Blay,Eric Demonsant,Pierre Diemunsch,Sophie Diemunsch,Renaud Felten,Bernard Goichot,Valentin Greigert,Aurélien Guffroy,Bob Heger,Anne Hutt,Charlotte Kaeuffer,Loic Kassegne,Anne Sophie Korganow,Pierrick Le Borgne,Nicolas Lefebvre,Tristan Martin,Paul Michel Mertes,Catherine Metzger,Nicolas Meyer,Gabriel Nisand,Eric Noll,Mathieu Oberlin,Sophie Ohlmann-Caillard,Vincent Poindron,Julien Pottecher,Yvon Ruch,Cédric Sublon,Hakim Tayebi,François Weill,Arsène Mekinian,Dorothée Chopin,Olivier Fain,Marc Garnier,Jessica Krause le Garrec,Marjolaine Morgand,Jérôme Pacanowski,Tomas Urbina,Chloe McAvoy,Maria Pereira,Gladys Aratus,Laurence Berard,Tabassome Simon,Anne Daguenel-Nguyen,Marie Antignac,Céline Leplay,Jean-Benoit Arlet,Jean-Luc Diehl,Florence Bellenfant,Anne Blanchard,Alexandre Buffet,Bernard Cholley,Antoine Fayol,Edouard Flamarion,Anne Godier,Thomas Gorget,Sophie-Rym Hamada,Caroline Hauw-Berlemont,Jean-Sébastien Hulot,David Lebeaux,Marine Livrozet,Adrien Michon,Arthur Neuschwander,Marie-Aude Penet,Benjamin Planquette,Brigitte Ranque,Olivier Sanchez,Geoffroy Volle,Sandrine Briois,Mathias Cornic,Virginie Elisee,Jesuthasan Denis,Juliette Djadi-Prat,Pauline Jouany,Ramon Junquera,Mickael Henriques,Amina Kebir,Isabelle Lehir,Jeanne Meunier,Florence Patin,Valérie Paquet,Anne Tréhan,Véronique Vigna,Brigitte Sabatier,Damien Bergerot,Charléne Jouve,Camille Knosp,Olivia Lenoir,Nassim Mahtal,Léa Resmini,F-Xavier Lescure,Jade Ghosn,Antoine Bachelard,Timothee Bironne,Raphael Borie,Agathe Bounhiol,Catherine Boussard,Jeanne CHAUFFiER,Solaya Chalal,Lynda Chalal,Malikhone Chansombat,Paul Crespin,Bruno Crestani,Olivia Daconceicao,Laurène Deconinck,Philippe Dieudé,A. Dossier,Marie Dubert,Greggory Ducrocq,Axelle Fuentes,A Gervais,Marie Gilbert,Valentina Isernia,Sophie Ismael,Veronique Joly,Z Julia,S Lariven,Sylvie Le Gac,Diane Le Pluart,F Louni,Awa Ndiaye,Thomas Papo,Marion Parisey,Bao Phung,Annabelle Pourbaix,Anne Rachline,C Rioux,Aurelie Sautereau,Gabriel Steg,Hassan Tarhini,Simon Valayer,Dorothee Vallois,Paul Vermes,Thomas Volpe,Yann Nguyen,Vasco Honsel,Emmanuel Weiss,Anaïs Codorniu,Virginie Zarrouk,Victoire De Lastours,Matthieu Uzzan,Olivier Olivier,Geoffrey Rossi,Naura Gamany,Roza Rahli,Zeina Louis,David Boutboul,Lionel Galicier,Yaël Amara,Gabrielle Archer,Amira Benattia,Anne Bergeron,Louise Bondeelle,Nathalie De Castro,Melissa Clément,Michaël Darmont,Blandine Denis,Clairelyne Dupin,Elsa Feredj,Delphine Feyeux,Adrien Joseph,Etienne Lengliné,Pierre Le Guen,Geoffroy Liégeon,Gwenaël Lorillon,Asmaa Mabrouki,Eric Mariotte,Grégoire Martin de Frémont,Adrien Mirouse,Jean-Michel Molina,Régis Peffault de Latour,Eric Oksenhendler,Julien Saussereau,Abdellatif Tazi,Jean-Jacques Tudesq,Lara Zafrani,Isabelle Brindele,Emmanuelle Bugnet,Karine Celli Lebras,Julien Chabert,Lalia Djaghout,Catherine Fauvaux,Anne Lise Jegu,Ewa Kozaliewicz,Martine Meunier,Marie-Thérèse Tremorin,Claire Davoine,Isabelle Madeleine,Sophie Caillat-Zucman,Constance Delaugerre,Florence Morin,Damien Sène,Ruxandra Burlacu,Benjamin G. Chousterman,Bruno Mégarbane,Pascal Richette,Jean-Pierre Riveline,Aline Frazier,Eric Vicaut,Laure Berton,Tassadit Hadjam,Miguel Alejandro Vasquez-Ibarra,Clément Jourdaine,Aude Jacob,Julie Smati,Stéphane Renaud,Philippe Manivet,Claire Pernin,Lydia Suarez,Luca Semerano,Sebastien Abad,Ruben Benainous,Coralie Bloch Queyrat,Nicolas Bonnet,Sabrina Brahmi,johann Cailhol,Yves Cohen,Celine Comparon,Hugues Cordel,Robin Dhote,Nathalie Dournon,B. Duchemann,Nathan Ebstein,Benedicte Giroux-Leprieur,Jeanne Goupil de Bouille,Anne Jacolot,Hilario Nunes,Johanna Oziel,Vanessa Rathouin,Marthe Rigal,Dominique Roulot,Claire Tantet,Yurdagul Uzunhan,Nathalie Costedoat-Chalumeau,Zakaria Ait Hamou,Sarah Benghanem,Philippe Blanche,Etienne Canouï,Nicolas Carlier,Benjamin Chaigne,Adrien Contejean,Bertrand Dunogue,Pierre Dupland,Aurélie Durel Maurisse,Rémy Gauzit,Paul Jaubert,Hassan Joumaa,Mathieu Jozwiak,Solen Kernéis,Marie Lachatre,Hélène Lafoeste,Paul Legendre,Liem Binh Luong Nguyen,Jonathan Marey,Caroline Morbieu,Luc Mouthon,Lee S. Nguyen,Lola-Jade Palmieri,Alexis Régent,Tali-Anne Szwebel,Benjamin Terrier,Corinne Guerin,Jérémie Zerbit,Kahina Cheref,Kamil Chitour,Mamadou Salif Cisse,Ada Clarke,Gaelle Clavere,Isabelle Dusanter,Caroline Gaudefroy,Moez Jallouli,Sami Kolta,Catherine Le Bourlout,Nathalie Marin,Nathalie Menage,Alexandre Moores,Isabelle Peigney,Cédric Pierron,Samira Saleh-Mghir,Mathilde Vallet,Marc Michel,Giovanna Melica,Jean-Daniel Lelievre,Elena Fois,Pascal Lim,Marie Matignon,Constance Guillaud,Alaki Thiemele,David Schmitz,Marion Bouhris,Syllia Belazouz,Laetitia Languille,Armand Mekontso-Dessaps,Thiziri Sadaoui,Julien Mayaux,Patrice Cacoub,Jean-Christophe Corvol,Céline Louapre,Sara Sambin,Louise-Laure Mariani,Carine Karachi,Florence Tubach,Candice Estellat,Linda Gimeno,Karine Martin,Aïcha Bah,Vixra Keo,Sabrine Ouamri,Yasmine Messaoudi,Nessima Yelles,Pierre Faye,Sébastien Cavelot,Cecile Larcheveque,Laurence Annonay,Jaouad Benhida,Aida Zahrate-Ghoul,Soumeya Hammal,Ridha Belilita,Marie Lecronier,Alexandra Beurton,Luc Haudebourg,Robin Deleris,Julien Le Marec,Sara Virolle,Safaa Nemlaghi,Côme Bureau,Pierre Mora,Martin De Sarcus,Olivier Clovet,Baptiste Duceau,Paul Henri Grisot,Marie hélène Pari,Jeremy Arzoine,Ulrich Clarac,Morgane Faure,Julie Delemazure,Maxence Decavele,Elise Morawiec,Alexandre Demoule,Martin Dres,Mathieu Vautier,Yves Allenbach,Olivier Benveniste,Gaelle Leroux,Aude Rigolet,Perrine Guillaume-Jugnot,Fanny Domont,Anne Claire Desbois,Cloé Comarmond,Nicolas Champtiaux,Segolene Toquet,Amine Ghembaza,Matheus Vieira,Georgina Maalouf,Gonçalo Boleto,Yasmina Ferfar,Fanny Charbonnier,Claire Aguilar,Fanny Alby-Laurent,Marie-Alexandra Alyanakian,Prissile Bakouboula,Christine Broissand,Carole Burger,Clara Campos-Vega,Nathalie Chavarot,Laure Choupeaux,Benjamin Fournier,Sophie Granville,Elodie Issorat,Claire Rouzaud,Damien Vimpere,Guillaume Geri,Nawal Derridj,Naima Sguiouar,Hakim Meddah,Mourad Djadel,Helene Chambrin-Lauvray,Jean-Charles Duclos-Vallée,Faouzi Saliba,Sophie-Caroline Sacleux,Ilias Koumis,Jean-Marie Michot,Annabelle Stoclin,Emeline Colomba,Fanny Pommeret,Chistophe Willekens,Madona Sakkal,Rosa Da Silva,Valérie Dejean,Yasmina Mekid,Ines Ben-Mabrouk,Caroline Pradon,Laurence Drouard,Valérie Camara-Clayette,Alexandre Morel,Gilles Garcia,Abolfazl Mohebbi,Férial Berbour,Mélanie Dehais,Anne-Lise Pouliquen,Alison Klasen,Loren Soyez-Herkert,Jonathan London,Younes Keroumi,Emmanuelle Guillot,Guillaume Grailles,Younes El Amine,Fanny Defrancq,Hanane Fodil,Chaouki Bouras,Dominique Dautel,Nicolas Gambier,Thierno Dieye,Anaïs Razurel,Boris Bienvenu,Victor Lancon,Laurence Lecomte,Kristina Beziriganyan,Belkacem Asselate,Laure Allanic,Elena Kiouris,Marie-Hélène Legros,Christine Lemagner,Pascal Martel,Vincent Provitolo,Félix Ackermann,Mathilde Le Marchand,Aurélie Clan Hew Wai,Dimitri Fremont,Elisabeth Coupez,Mireille Adda,Frédéric Duée,Lise Bernard,Antoine Gros,Estelle Henry,Claire Courtin,Anne Pattyn,Pierre-Grégoire Guinot,Marc Bardou,Agnes Maurer,Julie Jambon,Amélie Cransac,Corinne Pernot,Bruno Mourvillier,Amélie Servettaz,Gaëtan Deslée,Alain Wynckel,Philippe Benoit,Eric Marquis,Damien Roux,Coralie Gernez,Cécile Yelnik,Julien Poissy,Mandy Nizard,Fanette Denies,Hélène Gros,Jean-Jacques Mourad,Emmanuelle Sacco,Sophie Renet +600 more
TL;DR: Anakinra did not improve outcomes in patients with mild-to-moderate COVID-19 pneumonia, and further studies are needed to assess the efficacy of anakinra in other selected groups of patients with more severe CO VID-19.
Journal ArticleDOI
Remdesivir plus standard of care versus standard of care alone for the treatment of patients admitted to hospital with COVID-19 (DisCoVeRy): a phase 3, randomised, controlled, open-label trial.
Florence Ader,M. Bouscambert-Duchamp,Maya Hites,Nathan Peiffer-Smadja,Nathan Peiffer-Smadja,Julien Poissy,Drifa Belhadi,Alpha Diallo,Minh-Patrick Le,Gilles Peytavin,Thérèse Staub,Richard Greil,Jeremie Guedj,José Artur Paiva,Dominique Costagliola,Yazdan Yazdanpanah,Charles Burdet,Alexander Egle,Michael Joannidis,Bernd Lamprecht,Antoine Altdorfer,Leila Belkhir,Vincent Fraipont,Gil Verschelden,Jérôme Aboab,Hafid Ait-Oufella,Claire Andrejak,Pascal Andreu,Laurent Argaud,Firouzé Bani-Sadr,François Bénézit,M. Blot,Elisabeth Botelho-Nevers,Lila Bouadma,Olivier Bouchaud,David Bougon,Kevin Bouiller,Fanny Bounes-Vardon,David Boutoille,Alexandre Boyer,Cédric Bruel,André Cabié,Emmanuel Canet,Charles Cazanave,Cyrille Chabartier,Catherine Chirouze,Raphaël Clere-Jehl,Johan Courjon,Flora Crockett,François Danion,Agathe Delbove,Jean Dellamonica,F. Djossou,Clément Dubost,Alexandre Duvignaud,Olivier Epaulard,Loïc Epelboin,Murielle Fartoukh,Karine Faure,Emmanuel Faure,Tristan Ferry,Cécile Ficko,Samy Figueiredo,Benjamin Gaborit,Rostane Gaci,Amandine Gagneux-Brunon,Sébastien Gallien,Denis Garot,Guillaume Geri,Sébastien Gibot,François Goehringer,Marie Gousseff,Didier Gruson,Yves Hansmann,Olivier Hinschberger,Stéphane Jauréguiberry,Vanessa Jeanmichel,Solen Kernéis,Antoine Kimmoun,Kada Klouche,Marie Lachâtre,Karine Lacombe,Fabrice Laine,Jean-Philippe Lanoix,Odile Launay,Bruno Laviolle,Vincent Le Moing,Jérôme Le Pavec,Yves Le Tulzo,Paul Le Turnier,David Lebeaux,Benjamin Lefevre,Sylvie Leroy,François-Xavier Lescure,Henry Lessire,Benjamin Leveau,Paul Loubet,Alain Makinson,Denis Malvy,Charles-Hugo Marquette,Guillaume Martin-Blondel,Martin Martinot,Julien Mayaux,Armand Mekontso-Dessap,Ferhat Meziani,Jean-Paul Mira,Jean-Michel Molina,Xavier Monnet,Joy Mootien,Bruno Mourvillier,Marlène Murris-Espin,Jean-Christophe Navellou,Saad Nseir,Walid Oulehri,Thomas Perpoint,Gilles Pialoux,Benoit Pilmis,Vincent Piriou,Lionel Piroth,Valérie Pourcher,Jean-Pierre Quenot,François Raffi,Jean Reignier,Matthieu Revest,Jean-Christophe Richard,Béatrice Riu-Poulenc,Céline Robert,Pierre-Alexandre Roger,Claire Roger,Elisabeth Rouveix-Nordon,Yvon Ruch,Nadia Saidani,Naomi Sayre,Eric Senneville,Albert Sotto,Francois Stefan,Charles Tacquard,Nicolas Terzi,Julien Textoris,Guillaume Thiery,Jean-François Timsit,Violaine Tolsma,Jean-Marie Turmel,Florent Valour,Florent Wallet,Guilhem Wattecamps,Yoann Zerbib,Marc Berna,Jean Reuter,Sandra Braz,Joao-Miguel Ferreira Ribeiro,Roberto Roncon-Albuquerque,Alexandre Gaymard,Bruno Lina,Sarah Tubiana,Sandrine Couffin-Cadiergues,Hélène Espérou,Aline Dechanet,Christelle Delmas,Claire Fougerou,Noémie Mercier,Marion Noret,Juliette Saillard,Priyanka Velou +163 more
TL;DR: The DisCoVeRy trial as mentioned in this paper evaluated the clinical efficacy of remdesivir plus standard care compared with standard of care alone in patients admitted to hospital with COVID-19, with indication of oxygen or ventilator support.
Journal ArticleDOI
Campylobacter Bacteremia: Clinical Features and Factors Associated with Fatal Outcome
Jérôme Pacanowski,Valérie Lalande,Karine Lacombe,Karine Lacombe,Cherif Boudraa,Philippe Lesprit,Patrick Legrand,David Trystram,Najiby Kassis,Guillaume Arlet,Jean-Luc Mainardi,Florence Doucet-Populaire,Pierre-Marie Girard,Pierre-Marie Girard,Jean-Luc Meynard +14 more
TL;DR: Clinical features and risk factors of death differ by infection species, mainly in immunocompromised patients.