Alfred Walz

TL;DR: It has been shown that CSa, formylmethionyl peptides, PAF, and LTB4 act via unrelated receptors, suggesting that neutrophil recruitment can result from the concerted action of multiple stimuli.

TL;DR: A functional role of the ELR motif is suggested in determining the angiogenic or angiostatic potential of CXC chemokines, supporting the hypothesis that the net biological balance between angiogenicity and angiOSTatic CXCs may play an important role in regulating overall angiogenesis.

TL;DR: New insights into the role of chemokines in leukocytes attraction and relocation will be discussed, with emphasis on the distinct levels of leukocyte migration control that ultimately determine the performance of the immune defense system.

TL;DR: Evidence is provided of a relation between the presence of interleukin-8 in early BAL samples and the development of ARDS, which reinforces the likely importance of neutrophils and the effects of their accumulation and activation in the pathogenesis of many cases of AR DS.

TL;DR: The biological properties of a neutrophil-activating factor (NAF), which was recently identified as a novel peptide of approximately 6,000 mol wt, are described and the NAF receptor can be distinguished from the receptors of C5a, FMLP, platelet-activated factor, and leukotriene B4 by the lack of cross-desensitization.