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Ali S M Jawad

Researcher at Royal London Hospital

Publications -  117
Citations -  1601

Ali S M Jawad is an academic researcher from Royal London Hospital. The author has contributed to research in topics: Medicine & Rheumatoid arthritis. The author has an hindex of 20, co-authored 100 publications receiving 1308 citations. Previous affiliations of Ali S M Jawad include University of Cambridge & Royal College of Physicians.

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The effect of rheumatoid arthritis and steroid therapy on bone density in postmenopausal women

TL;DR: Osteoporosis in postmenopausal women with RA is more evident at the hip than the spine, and the most important determinants of bone loss are disability and cumulative corticosteroid dose.
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The effect of ethnicity and genetic ancestry on the epidemiology, clinical features and outcome of systemic lupus erythematosus.

TL;DR: Race/ethnicity remains a key determinant of poor outcome, such as end-stage renal failure and mortality, in SLE, and community measures to expedite diagnosis through increased awareness in at-risk racial/ethnic populations and ethnically personalized treatment algorithms may help in future to improve long-term outcomes inSLE.
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Incomplete response of inflammatory arthritis to TNFα blockade is associated with the Th17 pathway

TL;DR: Significant increases in circulating Th17 cells were observed in patients after anti-TNFα therapy and this was accompanied by increased production of IL-12/23p40, suggesting that a Th17-targeted therapeutic approach may be useful for anti- TNFα non-responder patients or as an adjunct to anti-tumour necrosis factor α therapy, provided that safety concerns can be addressed.
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Heterogeneous yet stable Vδ2(+) T-cell profiles define distinct cytotoxic effector potentials in healthy human individuals.

TL;DR: A significant variability in Vδ2(+) T-cell functional potential between individuals in the general population is revealed, which develops shortly after birth, is stable over time, and is manifested by differential mechanistic capacities to kill tumor targets.