A
Alida A. Gouw
Researcher at VU University Amsterdam
Publications - 84
Citations - 6446
Alida A. Gouw is an academic researcher from VU University Amsterdam. The author has contributed to research in topics: Hyperintensity & Cognitive decline. The author has an hindex of 35, co-authored 74 publications receiving 5053 citations. Previous affiliations of Alida A. Gouw include University of Amsterdam & University Medical Center Utrecht.
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Journal ArticleDOI
Preclinical Alzheimer's disease: Definition, natural history, and diagnostic criteria.
Bruno Dubois,Harald Hampel,Harald Hampel,Howard Feldman,Philip Scheltens,Paul S. Aisen,Sandrine Andrieu,Hovagim Bakardjian,Habib Benali,Lars Bertram,Lars Bertram,Kaj Blennow,Karl Broich,Enrica Cavedo,Sebastian J. Crutch,Jean-François Dartigues,Charles Duyckaerts,Stéphane Epelbaum,Giovanni B. Frisoni,Serge Gauthier,Remy Genthon,Alida A. Gouw,Alida A. Gouw,Marie-Odile Habert,David M. Holtzman,Miia Kivipelto,Miia Kivipelto,Simone Lista,José Luis Molinuevo,Sid E. O'Bryant,Gil D. Rabinovici,Christopher C. Rowe,Stephen Salloway,Lon S. Schneider,Reisa A. Sperling,Reisa A. Sperling,Marc Teichmann,Maria C. Carrillo,Jeffrey L. Cummings,Cliff R. Jack +39 more
TL;DR: An updated review of the literature and evidence on the definitions and lexicon, the limits, the natural history, the markers of progression, and the ethical consequence of detecting the disease at this asymptomatic stage of Alzheimer's disease are provided.
Journal ArticleDOI
Heterogeneity of small vessel disease: a systematic review of MRI and histopathology correlations
Alida A. Gouw,Alexandra Seewann,Wiesje M. van der Flier,Frederik Barkhof,Annemieke M. Rozemuller,Philip Scheltens,Jeroen J. G. Geurts +6 more
TL;DR: Pathological substrates of WMH are heterogeneous in nature and severity, which may partly explain the weak clinicoradiological associations found in SVD.
Journal ArticleDOI
Progression of white matter hyperintensities and incidence of new lacunes over a 3-year period: the Leukoaraiosis and Disability study.
Alida A. Gouw,W.M. van der Flier,Franz Fazekas,E.C.W. van Straaten,Leonardo Pantoni,Anna Poggesi,Domenico Inzitari,Timo Erkinjuntti,Lars-Olof Wahlund,Gunhild Waldemar,R. Schmidt,Philip Scheltens,Frederik Barkhof +12 more
TL;DR: WMH and lacunes progressed over time, predominantly in the subcortical white matter, and the presence of vascular risk factors at baseline predicted WMH progression and new lacunes over a 3-year period.
Journal ArticleDOI
Direction of information flow in large-scale resting-state networks is frequency-dependent
Arjan Hillebrand,Prejaas Tewarie,Edwin van Dellen,Meichen Yu,Ellen W. S. Carbo,Linda Douw,Alida A. Gouw,Elisabeth C.W. van Straaten,Cornelis J. Stam +8 more
TL;DR: The results provide evidence that large-scale resting-state patterns of information flow in the human brain form frequency-dependent reentry loops that are dominated by flow from parieto-occipital cortex to integrative frontal areas in the higher-frequency bands, which is mirrored by a theta band anterior-to-posterior flow.
Journal ArticleDOI
Heterogeneity of white matter hyperintensities in Alzheimer's disease: post-mortem quantitative MRI and neuropathology
Alida A. Gouw,Alexandra Seewann,Hugo Vrenken,W.M. van der Flier,J. M. Rozemuller,Frederik Barkhof,Philip Scheltens,Jeroen J. G. Geurts +7 more
TL;DR: Quantitative MRI techniques reveal differences in WMH between Alzheimer's disease and non-demented elderly, and are able to reflect the severity of the neuropathological changes involved.