A
Alina-Andreea Zimta
Researcher at Iuliu Hațieganu University of Medicine and Pharmacy
Publications - 42
Citations - 1030
Alina-Andreea Zimta is an academic researcher from Iuliu Hațieganu University of Medicine and Pharmacy. The author has contributed to research in topics: Cancer & microRNA. The author has an hindex of 14, co-authored 40 publications receiving 579 citations.
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Journal ArticleDOI
The Role of Nrf2 Activity in Cancer Development and Progression.
Alina-Andreea Zimta,Diana Cenariu,Alexandru Irimie,Lorand Magdo,Seyed Mohammad Nabavi,Atanas G. Atanasov,Ioana Berindan-Neagoe +6 more
TL;DR: Nrf2’s role in cancer prevention, diagnosis, prognosis, and therapy is still in its infancy, and the future strategic planning of Nrf2-based oncological approaches should also consider the complex interaction between NRF2 and its various activators and inhibitors.
Journal ArticleDOI
The Function of Non-Coding RNAs in Lung Cancer Tumorigenesis
Cornelia Braicu,Alina-Andreea Zimta,Antonia Harangus,Ioana Iurca,Ioana Iurca,Alexandru Irimie,Ovidiu Coza,Ioana Berindan-Neagoe +7 more
TL;DR: The following non-coding RNAs are identified as tumor suppressors or with tumor-promoting function and are of utmost importance to direct future research on lung cancer towards analyzing other RNA types for which the currently available data indicates that are essential at modulating lung tumorigenesis.
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CRISPR/Cas9: Transcending the Reality of Genome Editing.
Sergiu Chira,Diana Gulei,Amin Hajitou,Alina-Andreea Zimta,Pierre Cordelier,Ioana Berindan-Neagoe +5 more
TL;DR: Recent improvements in CRISPR/Cas9 design are summarized to overcome the limitations that have arisen from the nuclease activity of Cas9 and the influence of this technology in cancer research.
Journal ArticleDOI
An Emerging Class of Long Non-coding RNA With Oncogenic Role Arises From the snoRNA Host Genes.
Alina-Andreea Zimta,Adrian Bogdan Tigu,Cornelia Braicu,Cristina Stefan,Calin Ionescu,Ioana Berindan-Neagoe +5 more
TL;DR: Through literature research, it is found that silencing of SNHGs through small interfering RNAs or short hairpin RNAs is very effective in both in vitro and in vivo experiments by lowering the aggressiveness of solid cancers.
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Nanoscale delivery systems for microRNAs in cancer therapy.
Sanda Boca,Diana Gulei,Alina-Andreea Zimta,Anca Onaciu,Lorand Magdo,Adrian Bogdan Tigu,Calin Ionescu,Alexandru Irimie,Rares Buiga,Ioana Berindan-Neagoe +9 more
TL;DR: The present review presents the latest advancements in miRNA delivery based on nanoparticle-related strategies, which include inhibition of oncomiRNA expression and restoration of tumor suppressor ones.