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Allal Ouhtit
Researcher at Florida State University College of Arts and Sciences
Publications - 93
Citations - 3688
Allal Ouhtit is an academic researcher from Florida State University College of Arts and Sciences. The author has contributed to research in topics: Cancer & CD44. The author has an hindex of 32, co-authored 84 publications receiving 3128 citations. Previous affiliations of Allal Ouhtit include University of Texas MD Anderson Cancer Center & LSU Health Sciences Center New Orleans.
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Journal ArticleDOI
Fas ligand: a sensor for DNA damage critical in skin cancer etiology.
Laurie L. Hill,Allal Ouhtit,Susan M. Loughlin,Margaret L. Kripke,Honnavara N. Ananthaswamy,Laurie B. Owen-Schaub +5 more
TL;DR: Sunburn cell formation was found to be dependent on Fas ligand (FasL), a pro-apoptotic protein induced by DNA damage, suggesting that the dysregulation of Fas-Fasel interactions may be central to the development of skin cancer.
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Histopathological effects of cisplatin, doxorubicin and 5-flurouracil (5-FU) on the liver of male albino rats.
Hassan I. El-Sayyad,Mohamed Ismail,F M Shalaby,R F Abou-El-Magd,Rajiv L. Gaur,Augusta Fernando,Madhwa H.G. Raj,Allal Ouhtit +7 more
TL;DR: In vivo evidence, at ultrastructural level, of direct hepatotoxicity caused by cisplatin, doxorubicin and 5-FU is provided at both light and electron microscopi to guide the design of appropriate treatment regimen to reduce the hepatotoxic effects of these anticancer drugs.
Journal ArticleDOI
Mechanisms of induction of skin cancer by UV radiation.
TL;DR: The molecular events in the induction of skin cancer are being actively investigated, and recent research has added to the understanding of the roles of tumor suppressor and oncogenes in skin cancer.
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Temporal events in skin injury and the early adaptive responses in ultraviolet-irradiated mouse skin
Allal Ouhtit,H. Konrad Muller,Darren W. Davis,Stephen E. Ullrich,David J. McConkey,Honnavara N. Ananthaswamy +5 more
TL;DR: UV irradiation of mouse skin induces apoptosis mediated by the p53/p21/bax/bcl-2 pathway and that the dead cells are replaced by hyperproliferative cells, leading to epidermal hyperplasia implies that UV-induced apoptosis andhyperplasia are closely linked and tightly regulated and that dysregulation of these two events may lead to skin cancer development.
Journal ArticleDOI
Nanoparticle-mediated targeted drug delivery for breast cancer treatment.
Piumi Y. Liyanage,Sajini D. Hettiarachchi,Yiqun Zhou,Allal Ouhtit,Elif S. Seven,Cagri Oztan,Emrah Celik,Roger M. Leblanc +7 more
TL;DR: A critical analysis of the most recent therapeutic studies involving various NPs-mediated DDS as alternatives for the traditional treatment approaches for BC will shed light on the significance of N Ps- mediated DDS and serve as a guide to seeking for the ideal methodology for future targeted drug delivery for an efficient BC treatment.