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Allan Munck
Researcher at Dartmouth College
Publications - 97
Citations - 17668
Allan Munck is an academic researcher from Dartmouth College. The author has contributed to research in topics: Receptor & Glucocorticoid receptor. The author has an hindex of 48, co-authored 97 publications receiving 17030 citations. Previous affiliations of Allan Munck include University of Minnesota.
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Journal ArticleDOI
Interaction of glucocorticoids with macrophages. Identification of glucocorticoid receptors in monocytes and macrophages.
TL;DR: The results demonstrate that corticosteroids interact with macrophages at physiological concentrations, and dexamethasone to cytosol and nuclear forms of the receptor complex and temperature-sensitive translocation of cytOSol forms to nuclear forms were shown.
Journal ArticleDOI
Prostaglandin inhibition of T-cell proliferation is mediated at two levels.
TL;DR: The prostaglandin-E-mediated suppression of lectin-initiated T- cell proliferation could be traced to an inhibition of both the production and action of the T-cell-specific mitogen, TCGF.
Journal ArticleDOI
The ups and downs of glucocorticoid physiology. Permissive and suppressive effects revisited.
Journal ArticleDOI
Glucocorticoid receptors and glucocorticoid sensitivity of mitogen stimulated and unstimulated human lymphocytes
TL;DR: It is shown that prednisolone-21-phosphate inhibited incorporation of radiolabelled thymidine and cytidine into PHA-stimulated lymphocytes, and found that delayed addition of steroid resulted in diminished inhibition.
Book ChapterDOI
Glucocorticoid physiology, pharmacology and stress
Allan Munck,Paul M. Guyre +1 more
TL;DR: It is suggested that stress-induced increases in glucocorticoid levels protect not against the source of stress itself but rather against the body's normal reactions to stress, preventing those reactions from overshooting and themselves threatening homeostasis.