A
Alvaro Martinez-Barrio
Researcher at Uppsala University
Publications - 6
Citations - 827
Alvaro Martinez-Barrio is an academic researcher from Uppsala University. The author has contributed to research in topics: Population & Genome. The author has an hindex of 4, co-authored 5 publications receiving 687 citations.
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Journal ArticleDOI
Evolution of Darwin’s finches and their beaks revealed by genome sequencing
Sangeet Lamichhaney,Jonas Berglund,Markus Sällman Almén,Khurram Maqbool,Manfred Grabherr,Alvaro Martinez-Barrio,Marta Promerová,Carl-Johan Rubin,Chao Wang,Neda Zamani,B. Rosemary Grant,Peter R. Grant,Matthew T. Webster,Leif Andersson +13 more
TL;DR: The whole-genome re-sequencing of 120 individuals representing all of the Darwin’s finch species and two close relatives finds extensive evidence for interspecific gene flow throughout the radiation.
Journal ArticleDOI
RAD Sequencing and a Hybrid Antarctic Fur Seal Genome Assembly Reveal Rapidly Decaying Linkage Disequilibrium, Global Population Structure and Evidence for Inbreeding.
Emily Humble,Kanchon K. Dasmahapatra,Alvaro Martinez-Barrio,Inês Gregório,Jaume Forcada,Ann-Christin Polikeit,Simon D. Goldsworthy,Michael E. Goebel,Jörn Kalinowski,Jochen B. W. Wolf,Jochen B. W. Wolf,Joseph I. Hoffman +11 more
TL;DR: It is found that LD decayed rapidly, reaching the background level by around 400 kb, consistent with other vertebrates but at odds with the notion that fur seals experienced a strong historical bottleneck, and is a clear example of how high throughput sequencing can generate diverse biological insights at multiple levels of organization.
Journal ArticleDOI
A draft fur seal genome provides insights into factors affecting SNP validation and how to mitigate them
Emily Humble,Alvaro Martinez-Barrio,Jaume Forcada,Philip N. Trathan,Michael A. S. Thorne,M. Hoffmann,Jochen B. W. Wolf,Joseph I. Hoffman +7 more
TL;DR: Reanalysis of genotyping data from seven previous studies found the same two variables to be significantly associated with SNP validation success across a variety of taxa, indicating that sequence uniqueness and proximity to intron–exon boundaries play an important role.
Journal ArticleDOI
The methylation landscape and its role in domestication and gene regulation in the chicken.
Andrey Höglund,Rie Henriksen,Jesper Fogelholm,Allison M. Churcher,Carlos Guerrero-Bosagna,Carlos Guerrero-Bosagna,Alvaro Martinez-Barrio,Martin Johnsson,Martin Johnsson,Per Jensen,Dominic Wright +10 more
TL;DR: A role for methylation in the regulation of gene expression underlying the domesticated phenotype of the chicken is suggested and it is shown that methylation is correlated with some aspects of behavioural variation in the inter-cross.
Posted ContentDOI
RAD sequencing and a hybrid Antarctic fur seal genome assembly reveal rapidly decaying linkage disequilibrium, global population structure and evidence for inbreeding
Emily Humble,Kanchon K. Dasmahapatra,Alvaro Martinez-Barrio,Inês Gregório,Jaume Forcada,Ann-Christin Polikeit,Simon D. Goldsworthy,Michael E. Goebel,Jörn Kalinowski,Jochen B. W. Wolf,Jochen B. W. Wolf,Joseph I. Hoffman +11 more
TL;DR: Focusing on the most extensively sampled population of South Georgia, it was found that LD decayed rapidly, reaching the background level of r2 = 0.09 by around 26 kb, consistent with other vertebrates but at odds with the notion that fur seals experienced a strong historical bottleneck.