M
Markus Sällman Almén
Researcher at Uppsala University
Publications - 44
Citations - 4231
Markus Sällman Almén is an academic researcher from Uppsala University. The author has contributed to research in topics: Gene & Genome-wide association study. The author has an hindex of 24, co-authored 44 publications receiving 3685 citations. Previous affiliations of Markus Sällman Almén include Science for Life Laboratory.
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Trends in the exploitation of novel drug targets
TL;DR: The drugs that were approved by the US Food and Drug Administration during the past three decades are analysed and the interactions of these drugs with therapeutic targets that are encoded by the human genome are examined, using the DrugBank database and extensive manual curation.
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Evolution of Darwin’s finches and their beaks revealed by genome sequencing
Sangeet Lamichhaney,Jonas Berglund,Markus Sällman Almén,Khurram Maqbool,Manfred Grabherr,Alvaro Martinez-Barrio,Marta Promerová,Carl-Johan Rubin,Chao Wang,Neda Zamani,B. Rosemary Grant,Peter R. Grant,Matthew T. Webster,Leif Andersson +13 more
TL;DR: The whole-genome re-sequencing of 120 individuals representing all of the Darwin’s finch species and two close relatives finds extensive evidence for interspecific gene flow throughout the radiation.
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Mapping the human membrane proteome: a majority of the human membrane proteins can be classified according to function and evolutionary origin
TL;DR: It is estimated that 27% of the total human proteome are alpha-helical transmembrane proteins and this work provides an extended classification together with in-depth investigations of the membrane proteome's functional, structural, and evolutionary features.
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Acute sleep deprivation enhances the brain's response to hedonic food stimuli: an fMRI study.
Christian Benedict,Samantha J. Brooks,Owen O'Daly,Markus Sällman Almén,Arvid Morell,Karin Åberg,Malin Gingnell,Bernd Schultes,Manfred Hallschmid,Jan-Erik Broman,Elna-Marie Larsson,Helgi B. Schiöth +11 more
TL;DR: Examination of brain activation after sleep and sleep deprivation in response to images of food provides evidence that acute sleep loss enhances hedonic stimulus processing in the brain underlying the drive to consume food, independent of plasma glucose levels.
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A beak size locus in Darwin’s finches facilitated character displacement during a drought
Sangeet Lamichhaney,Fan Han,Jonas Berglund,Chao Wang,Markus Sällman Almén,Matthew T. Webster,B. Rosemary Grant,Peter R. Grant,Leif Andersson,Leif Andersson,Leif Andersson +10 more
TL;DR: A genome-wide analysis in finches identifies loci associated with parallel size variation in the Galápagos and discovered a genomic region containing the HMGA2 gene that varies systematically among Darwin’s finch species with different beak sizes.