A
Alvin Gomez
Researcher at University of Toronto
Publications - 26
Citations - 3189
Alvin Gomez is an academic researcher from University of Toronto. The author has contributed to research in topics: Aryl hydrocarbon receptor & DNA methylation. The author has an hindex of 19, co-authored 26 publications receiving 2963 citations. Previous affiliations of Alvin Gomez include University of Massachusetts Medical School & Karolinska Institutet.
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Influence of cytochrome P450 polymorphisms on drug therapies: Pharmacogenetic, pharmacoepigenetic and clinical aspects
TL;DR: It is concluded that the pharmacogenetic knowledge regarding CYP polymorphism now developed to a stage where it can be implemented in drug development and in clinical routine for specific drug treatments, thereby improving the drug response and reducing costs for drug treatment.
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Microbial diversity of hydrothermal sediments in the Guaymas Basin: evidence for anaerobic methanotrophic communities.
Andreas P Teske,Kai-Uwe Hinrichs,Virginia P. Edgcomb,Alvin Gomez,David T. Kysela,Sean P. Sylva,Mitchell L. Sogin,Holger W. Jannasch +7 more
TL;DR: The combined evidence from bacterial phylogeny and molecular-isotopic data indicates an important role of some novel deeply branching bacteria in anaerobic methanotrophy in the trophic ecology of methane-rich hydrothermal vents.
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Benthic eukaryotic diversity in the Guaymas Basin hydrothermal vent environment.
TL;DR: By using sequence comparisons of PCR-amplified small subunit ribosomal RNAs, eukaryotic diversity in hydrothermal vent environments of Guaymas Basin in the Gulf of California is characterized and the adaptation to anoxic environments is evidenced by specific affinity of environmental sequences to aerotolerant anaerobic species in molecular trees.
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Stable C0T-1 Repeat RNA Is Abundant and Is Associated with Euchromatic Interphase Chromosomes
Lisa L. Hall,Dawn M. Carone,Alvin Gomez,Heather J. Kolpa,Meg Byron,Nitish Mehta,Frank O. Fackelmayer,Jeanne B. Lawrence +7 more
TL;DR: C0T-1 RNA has several properties similar to XIST chromosomal RNA but is excluded from chromatin condensed by XIST, which impact two "black boxes" of genome science: the poorly understood diversity of noncoding RNA and the unexplained abundance of repetitive elements.
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Molecular genetics and epigenetics of the cytochrome P450 gene family and its relevance for cancer risk and treatment
TL;DR: It is concluded that the CYP polymorphism does not predict cancer susceptibility to any large extent but that this polymorphism might be an important factor for optimal cancer therapy using selected anticancer agents.