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AM Prieur

Researcher at Necker-Enfants Malades Hospital

Publications -  30
Citations -  2840

AM Prieur is an academic researcher from Necker-Enfants Malades Hospital. The author has contributed to research in topics: Juvenile rheumatoid arthritis & Neonatal onset multisystem inflammatory disease. The author has an hindex of 20, co-authored 30 publications receiving 2703 citations. Previous affiliations of AM Prieur include University of Paris.

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A randomized, placebo‐controlled trial of infliximab plus methotrexate for the treatment of polyarticular‐course juvenile rheumatoid arthritis

TL;DR: Safety data indicated that the 6-mg/kg dose may provide a more favorable risk/benefit profile for infliximab in the treatment of juvenile rheumatoid arthritis, and achievement of the primary efficacy end point at 3 months did not differ significantly between inflIXimab-treated and placebo-treated patients.
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Reactive haemophagocytic syndrome in children with inflammatory disorders. A retrospective study of 24 patients

TL;DR: RHS may be a more common complication of systemic disease in childhood than previously thought and calls for the immediate withdrawal of potentially triggering medications, anti-infective therapy when relevant, and urgent immunosuppressive treatment, measures that are very often effective.
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Randomized, placebo-controlled, crossover trial of low-dose oral methotrexate in children with extended oligoarticular or systemic arthritis.

TL;DR: MTX 15-20 mg/m2 given orally once a week was found to be an effective treatment for both extended oligoarticular and systemic JIA in this shortterm trial and long-term efficacy needs to be addressed in future studies.
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A chronic, infantile, neurological, cutaneous and articular (CINCA) syndrome. A specific entity analysed in 30 patients.

TL;DR: A high frequency of prematurity with features resembling a foetal infection was observed but no proof of a possible causal virus has so far been found so that etiology remains unknown.
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Long-term efficacy of the interleukin-1 receptor antagonist anakinra in ten patients with neonatal-onset multisystem inflammatory disease/chronic infantile neurologic, cutaneous, articular syndrome.

TL;DR: The present results indicate that anakinra treatment is effective over the long term in NOMID/CINCA syndrome, however, treatment has to be initiated before irreversible lesions develop, and, particularly in very young patients, dosage adjustment is required.