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Barry L. Myones
Researcher at Baylor College of Medicine
Publications - 27
Citations - 1714
Barry L. Myones is an academic researcher from Baylor College of Medicine. The author has contributed to research in topics: Lupus erythematosus & Systemic lupus erythematosus. The author has an hindex of 17, co-authored 27 publications receiving 1596 citations. Previous affiliations of Barry L. Myones include Boston Children's Hospital.
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Journal ArticleDOI
A randomized, placebo‐controlled trial of infliximab plus methotrexate for the treatment of polyarticular‐course juvenile rheumatoid arthritis
Nicolino Ruperto,Daniel J. Lovell,Ruben Cuttica,Nick Wilkinson,Patricia Woo,Graciela Espada,Carine Wouters,Earl D. Silverman,Zsolt Balogh,Michael Henrickson,Maria Teresa Apaz,Eileen Baildam,Anders Fasth,Valeria Gerloni,Pekka Lahdenne,AM Prieur,Angelo Ravelli,Rotraud K. Saurenmann,M.L. Gamir,Nico M Wulffraat,László Maródi,Ross E. Petty,Rik Joos,Francesco Zulian,Deborah McCurdy,Barry L. Myones,K. Nagy,Peter Reuman,Ilona S. Szer,Suzanne Travers,A. Beutler,Greg Keenan,Jason Clark,Sudha Visvanathan,Adedigbo A. Fasanmade,Aparna Raychaudhuri,Alan M. Mendelsohn,Alberto Martini,Edward H. Giannini +38 more
TL;DR: Safety data indicated that the 6-mg/kg dose may provide a more favorable risk/benefit profile for infliximab in the treatment of juvenile rheumatoid arthritis, and achievement of the primary efficacy end point at 3 months did not differ significantly between inflIXimab-treated and placebo-treated patients.
Journal ArticleDOI
Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus
Chaim O. Jacob,Jiankun Zhu,Don Armstrong,Don Armstrong,Mei Yan,Jie Han,Xin J. Zhou,James Thomas,Andreas Reiff,Barry L. Myones,Joshua O. Ojwang,Kenneth M. Kaufman,Marisa S. Klein-Gitelman,Deborah McCurdy,Linda Wagner-Weiner,Earl D. Silverman,Julie T. Ziegler,Jennifer A. Kelly,Joan T. Merrill,John B. Harley,Rosalind Ramsey-Goldman,Luis M. Vilá,Sang Cheol Bae,Timothy J. Vyse,Gary S. Gilkeson,Patrick M. Gaffney,Kathy L. Moser,Carl D. Langefeld,Raphael Zidovetzki,Chandra Mohan +29 more
TL;DR: The forward genetic studies in human SLE and the mechanistic studies in mouse models establish IRAK1 as a disease gene in lupus, capable of modulating at least 2 key checkpoints in disease development.
Journal ArticleDOI
Lupus-associated causal mutation in neutrophil cytosolic factor 2 (NCF2) brings unique insights to the structure and function of NADPH oxidase
Chaim O. Jacob,Miriam Eisenstein,Mary C. Dinauer,Wenyu Ming,Qiang Liu,Sutha John,Francesco P. Quismorio,Andreas Reiff,Barry L. Myones,Kenneth M. Kaufman,Deborah McCurdy,John B. Harley,Earl D. Silverman,Robert P. Kimberly,Timothy J. Vyse,Patrick M. Gaffney,Kathy L. Moser,Marisa S. Klein-Gitelman,Linda Wagner-Weiner,Carl D. Langefeld,Don Armstrong,Don Armstrong,Raphael Zidovetzki,Raphael Zidovetzki +23 more
TL;DR: A multidisciplinary approach is presented resulting in the identification of neutrophil cytosolic factor 2 (NCF2) as an important risk factor for SLE and the detailed characterization of its causal variant.
Journal ArticleDOI
Classification, presentation, and initial treatment of Wegener's granulomatosis in childhood
David A. Cabral,América G. Uribe,Susanne M. Benseler,Kathleen M. O'Neil,Philip J. Hashkes,Gloria C. Higgins,Andrew Zeft,Daniel J. Lovell,Daniel J. Kingsbury,Anne M. Stevens,Deborah McCurdy,Peter Chira,Leslie Abramson,Thaschawee Arkachaisri,Sarah Campillo,Anne Eberhard,Aimee O. Hersh,Adam M. Huber,Susan Kim,Marisa S. Klein-Gitelman,Deborah M. Levy,Suzanne C. Li,Thomas G. Mason,Esi Morgan DeWitt,Eyal Muscal,Lorien Nassi,Andreas Reiff,Kenneth N. Schikler,Nora G. Singer,Dawn M. Wahezi,Amy Woodward,Victor Espinosa,Jaime Guzman,Kristin Houghton,Peter N. Malleson,Ross E. Petty,Lori B. Tucker,Stuart E. Turvey,Elizabeth B. Brooks,Mary Lesko,Fatma Dedeoglu,Robert C. Fuhlbrigge,Melissa M. Hazen,Mary Beth F. Son,Robert P. Sundel,Diane E. Brown,Bracha Shaham,Ana Cabrera,Norman T. Ilowite,Raphael Hirsh,Daniel Kietz,Paul Rosen,Margalit Rosenkrank,Kathryn S. Torok,Lauren M. Pachman,Aisha Ali,Hermine I. Brunner,Thomas A. Griffin,A. Grom,Anne Johnson,Steven J. Spalding,Deborah Bork,Stacy P. Ardoin,Egla Rabinovich,Laura E. Schanberg,Rhonda Wilder,Bianca A. Lang,Suzanne E. Ramsey,Elizabeth Stringer,Aleasha Warner,Kathleen A. Haines,Yukiko Kimura,J Weiss,Imelda Balboni,Reuven Bromberg,Michal Cidon,Jennifer Frankovich,Dana Gerstbacher,Joyce J. Hsu,Tzielan Lee,Jane L. Park,Christy Sandborg,Steven J. Song,Ann M. Reed,Gaëlle Chédeville,Ciarán M. Duffy,Karen Watanabe Duffy,Rosie Scuccimarri,Michele Gibbon,Andrew H. Eichenfield,Lisa Imundo,Candido Batres,Suzanne L. Bowyer,Susan H. Ballinger,Thomas Klausmeier,Andrea Hudgins,Helen Emery,Kristin Hayward,Christi J. Inman,Sarah Ringold,Elizabeth A. Shaw,Troy R. Torgerson,Jennifer Turner,Carol A. Wallace,Jennifer Wargula,Sarah Halford,Barry L. Myones,Marilynn Punaro,Virginia Pascual,Emily von Scheven,Adrienne Michels,Michael Henrickson,James N. Jarvis,John Bonsack,S Prahalad +114 more
TL;DR: The EULAR/PRES criteria minimally improved diagnostic sensitivity and specificity for Wegener's granulomatosis among a narrow spectrum of children with AAVs.
Journal ArticleDOI
Frequency of antibodies to the cholesterol transport protein apolipoprotein A1 in patients with SLE.
TL;DR: The high prevalence of antibodies to apoA1 in patients with systemic lupus and suggests a high affinity of these antibodies for mature HDL for nascent or mature high-density lipoprotein (HDL) is confirmed.