Amanda H. Mahnke

TL;DR: Experimental evidence supports the inclusion of sex as a variable in the study of a number of novel stroke drugs and therapies, including preclinical studies of anti‐inflammatory drugs (minocycline), stimulators of cell survival (insulin‐like growth factor‐1), and inhibitors of cell death pathways (pharmacological inhibition of poly[ADP‐ribose] polymerase‐1, nitric oxide production, and caspase activation).

TL;DR: The data indicate that VGLUT2 expression is pivotal to the proper development of mature pyramidal neuronal architecture and plasticity, and that such glutamatergic deficiency leads to cognitive malfunction as observed in several neurodevelopmental psychiatric disorders.

TL;DR: It is suggested that AMPA receptor expression is an important determinant of dendrite morphology and connectivity in neocortical neurons, and that contrary to other regions of the CNS, the effects of AMPA receptors on dendritic morphology are not subunit-specific.

TL;DR: It is shown that epigenetic modifications change global gene expression in response to environmental factors and can be a positive or negative sign for cancer diagnosis.

TL;DR: It is reported for the first time that PAE inhibits expression of placental pro-EMT pathway members in both rodents and primates, and that HEamiRNAs collectively, but not individually, mediate placental EMT inhibition.