A
Amarsanaa Jazag
Researcher at University of Tokyo
Publications - 26
Citations - 1650
Amarsanaa Jazag is an academic researcher from University of Tokyo. The author has contributed to research in topics: Gene knockdown & RNA interference. The author has an hindex of 17, co-authored 26 publications receiving 1556 citations.
Papers
More filters
Journal ArticleDOI
Functional analysis of PIK3CA gene mutations in human colorectal cancer.
Tsuneo Ikenoue,Fumihiko Kanai,Yohko Hikiba,Toshiyuki Obata,Yasuo Tanaka,Jun Imamura,Miki Ohta,Amarsanaa Jazag,Bayasi Guleng,Keisuke Tateishi,Yoshinari Asaoka,Masayuki Matsumura,Takao Kawabe,Masao Omata +13 more
TL;DR: Results show that almost all the colon cancer-associated PIK3CA mutations are functionally active so that they are likely to be involved in carcinogenesis.
Journal ArticleDOI
Blockade of the Stromal Cell–Derived Factor-1/CXCR4 Axis Attenuates In vivo Tumor Growth by Inhibiting Angiogenesis in a Vascular Endothelial Growth Factor–Independent Manner
Bayasi Guleng,Keisuke Tateishi,Miki Ohta,Fumihiko Kanai,Amarsanaa Jazag,Hideaki Ijichi,Yasuo Tanaka,Miwa Washida,Keita Morikane,Yasushi Fukushima,Takao Yamori,Takashi Tsuruo,Takao Kawabe,Makoto Miyagishi,Kazunari Taira,Masataka Sata,Masao Omata +16 more
TL;DR: The data indicate that the SDF-1/CXCR4 pathway might be a general target for anticancer strategies and that blocking this system could be cooperatively effective in combination with other antiangiogenic therapies, such as blockade of VEGF.
Journal ArticleDOI
Hepatitis C Virus Core Protein Is a Potent Inhibitor of RNA Silencing-Based Antiviral Response
Yue Wang,Naoya Kato,Amarsanaa Jazag,Narayan Dharel,Motoyuki Otsuka,Hiroyoshi Taniguchi,Takao Kawabe,Masao Omata +7 more
TL;DR: RNAi is a limiting factor for HCV infection, and the core protein suppresses the RNA silencing-based antiviral response, which may lead to a persistent viral infection and may contribute to the pathogenesis of HCV.
Journal ArticleDOI
The hepatitis B virus X protein enhances AP-1 activation through interaction with Jab1.
Yasuo Tanaka,Fumihiko Kanai,Tohru Ichimura,Keisuke Tateishi,Yoshinari Asaoka,Bayasi Guleng,Amarsanaa Jazag,Miki Ohta,Jun Imamura,Tsuneo Ikenoue,Hideaki Ijichi,Takao Kawabe,Toshiaki Isobe,Masao Omata +13 more
TL;DR: Results suggest that the interaction between HBx and Jab1 enhances HBx-mediated AP-1 activation.
Journal ArticleDOI
HMGA1 Is a Determinant of Cellular Invasiveness and In vivo Metastatic Potential in Pancreatic Adenocarcinoma
TL;DR: The findings suggest that HMGA1 may be a novel molecular determinant of invasiveness and metastasis, as well as a potential therapeutic target, in pancreatic adenocarcinoma.