A
Amina Barhdadi
Researcher at Montreal Heart Institute
Publications - 27
Citations - 1177
Amina Barhdadi is an academic researcher from Montreal Heart Institute. The author has contributed to research in topics: Population & Calcineurin. The author has an hindex of 14, co-authored 26 publications receiving 940 citations. Previous affiliations of Amina Barhdadi include Université de Montréal.
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Journal ArticleDOI
Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy.
Colin J. D. Ross,Colin J. D. Ross,Hagit Katzov-Eckert,Hagit Katzov-Eckert,Marie-Pierre Dubé,Beth Brooks,S. Rod Rassekh,Amina Barhdadi,Yassamin Feroz-Zada,Henk Visscher,Henk Visscher,Andrew M.K. Brown,Michael J. Rieder,Paul Rogers,Michael S. Phillips,Bruce Carleton,Bruce Carleton,Michael R. Hayden,Michael R. Hayden +18 more
TL;DR: Association analyses for 220 drug-metabolism genes in genetic susceptibility to cisplatin-induced hearing loss in children are reported and genetic variants in TPMT and COMT are identified associated with cisPlatin- induced hearing Loss in children.
Journal ArticleDOI
DNMT3A and TET2 dominate clonal hematopoiesis and demonstrate benign phenotypes and different genetic predispositions.
Manuel Buscarlet,Sylvie Provost,Yassamin Feroz Zada,Amina Barhdadi,Vincent Bourgoin,Guylaine Lépine,Luigina Mollica,Luigina Mollica,Natasha Szuber,Natasha Szuber,Marie-Pierre Dubé,Marie-Pierre Dubé,Lambert Busque,Lambert Busque +13 more
TL;DR: The discordance between the high prevalence of mutations in these 2 genes and their limited biological impact raise the question of the potential role of dysregulated epigenetic modifiers in normal aging hematopoiesis, which may include support to failing hematosynthesis.
Journal ArticleDOI
DNA methylation signature of human fetal alcohol spectrum disorder
Elodie Portales-Casamar,Alexandre A. Lussier,Meaghan J. Jones,Julia L. MacIsaac,Rachel D. Edgar,Sarah M Mah,Amina Barhdadi,Sylvie Provost,Louis-Philippe Lemieux-Perreault,Max S. Cynader,Albert E. Chudley,Marie-Pierre Dubé,Marie-Pierre Dubé,James N. Reynolds,Paul Pavlidis,Michael S. Kobor +15 more
TL;DR: It is suggested that prenatal alcohol exposure is associated with distinct DNA methylation patterns in children and adolescents, raising the possibility of an epigenetic biomarker of FASD.
Journal ArticleDOI
Family Study of Restless Legs Syndrome in Quebec, Canada Clinical Characterization of 671 Familial Cases
Lan Xiong,Jacques Montplaisir,Alex Desautels,Amina Barhdadi,Gustavo Turecki,Anastasia Levchenko,Pascale Thibodeau,Marie-Pierre Dubé,Claudia Gaspar,Guy A. Rouleau +9 more
TL;DR: The clinical data indicated that fRLS is more prominent among women who also had increased incidence of anemia/iron deficiency, arthritis, and number of pregnancies, and afflicted women tend to have a much younger age of onset.
Journal ArticleDOI
Methylomic changes during conversion to psychosis.
Oussama Kebir,Boris Chaumette,Fabrice Rivollier,F Miozzo,F Miozzo,L P Lemieux Perreault,Amina Barhdadi,Sylvie Provost,Marion Plaze,Julie Bourgin,Célia Mam-Lam-Fook,Charlotte Alexandre,Charlotte Alexandre,Emilie Magadu,Gilles Martinez,M. Kazes,Mélanie Chayet,Zelda Prost,Raphaël Gaillard,V Mezger,V Mezger,M-P Dubé,M-O Krebs +22 more
TL;DR: In this first study of methylation during conversion to psychosis, it is found that alterations preferentially occurred in gene promoters and pathways relevant for psychosis, including oxidative stress regulation, axon guidance and inflammatory pathways.