A
Anastasia Levchenko
Researcher at Université de Montréal
Publications - 14
Citations - 579
Anastasia Levchenko is an academic researcher from Université de Montréal. The author has contributed to research in topics: Gene & BTBD9. The author has an hindex of 8, co-authored 11 publications receiving 552 citations. Previous affiliations of Anastasia Levchenko include McGill University & McGill University Health Centre.
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Journal ArticleDOI
A novel autosomal dominant restless legs syndrome locus maps to chromosome 20p13
Anastasia Levchenko,Sylvie Provost,Jacques Montplaisir,Lan Xiong,Judith St-Onge,Pascale Thibodeau,Jean-Baptiste Rivière,Alex Desautels,Gustavo Turecki,Marie-Pierre Dubé,Guy A. Rouleau +10 more
TL;DR: The authors investigated genetic factors contributing to restless legs syndrome by performing a 10-cM genome-wide scan in a large French-Canadian pedigree and detected an autosomal-dominant locus mapping to chromosome 20p13, with a maximum multipoint lod score of 3.86.
Journal ArticleDOI
The 14q restless legs syndrome locus in the French Canadian population.
Anastasia Levchenko,Jacques-Yves Montplaisir,Marie-Pierre Dubé,Jean-Baptiste Rivière,Judith St-Onge,Gustavo Turecki,Lan Xiong,Pascale Thibodeau,Alex Desautels,Dominique J. Verlaan,Guy A. Rouleau +10 more
TL;DR: A new restless legs syndrome locus on chromosome 14 recently has been reported in one family of Italian origin, providing support for the existence of this locus and indicating thatThis locus may be responsible for a small fraction of French Canadian restless Legs syndrome.
Journal ArticleDOI
MEIS1 intronic risk haplotype associated with restless legs syndrome affects its mRNA and protein expression levels
Lan Xiong,Hélène Catoire,Patrick A. Dion,Claudia Gaspar,Ronald G. Lafrenière,Simon Girard,Anastasia Levchenko,Jean Baptiste Rivière,Laura M. Fiori,Judith St-Onge,Isabelle Bachand,Pascale Thibodeau,Richard P. Allen,Christopher J. Earley,Gustavo Turecki,Jacques Montplaisir,Guy A. Rouleau +16 more
TL;DR: Data suggest that reduced expression of the MEIS1 gene, possibly through intronic cis-regulatory element(s), predisposes to RLS.
Journal ArticleDOI
Family Study of Restless Legs Syndrome in Quebec, Canada Clinical Characterization of 671 Familial Cases
Lan Xiong,Jacques Montplaisir,Alex Desautels,Amina Barhdadi,Gustavo Turecki,Anastasia Levchenko,Pascale Thibodeau,Marie-Pierre Dubé,Claudia Gaspar,Guy A. Rouleau +9 more
TL;DR: The clinical data indicated that fRLS is more prominent among women who also had increased incidence of anemia/iron deficiency, arthritis, and number of pregnancies, and afflicted women tend to have a much younger age of onset.
Journal ArticleDOI
Canadian restless legs syndrome twin study.
Lan Xiong,K. Jang,Jacques Montplaisir,Anastasia Levchenko,Pascale Thibodeau,Claudia Gaspar,Gustavo Turecki,Guy A. Rouleau +7 more
TL;DR: A validated 36-item RLS questionnaire, used for family studies of RLS4 and reformatted to be self-administered, and a standard zygosity questionnaire were individually mailed to 600 adult co-twins from the University of British Columbia twin registry across Canada.